It is well-known that the utilization of mushrooms as therapeutic agents is not new. Over the
past years, they have been used by local individuals as food, as well as medicines …

Population movements have turned Chagas disease (CD) into a global public health
problem. Despite the successful implementation of subregional initiatives to control vectorial …

Background: Benznidazole is recommended for treatment of Chagas infection. Effects of
combination therapy with benznidazole and posaconazole have not been tested in …

The haemoflagellate protozoan Trypanosoma cruzi (T. cruzi) is the causative agent of
Chagas disease (CD), a potentially life-threatening disease. Little by little, remarkable …

Chagas disease, leishmaniasis and schistosomiasis are neglected diseases (NDs) and are
a considerable global challenge. Despite the huge number of people infected, NDs do not …

Human trypanosomiasis and leishmaniasis are vector‐borne neglected tropical diseases
caused by infection with the protozoan parasites Trypanosoma spp. and Leishmania spp …

Abstract Purpose of Review Chagas disease (CD) is endemic to much of Latin America, but
also present in the United States (US). Following a lengthy asymptomatic period, CD …

Chagas disease (CD) is a centenarian neglected parasitosis caused by the protozoan
Trypanosoma cruzi (T. cruzi). Despite the continuous efforts of many organizations and …

Nitriles have broad applications in medicinal chemistry, with more than 60 small molecule
drugs on the market containing the cyano functional group. In addition to the well-known …

Parasitic protozoan diseases continue to rank among the world's greatest global health
problems, which are also common among poor populations. Currently available drugs for …