Exosomes and breast cancer drug resistance
Drug resistance is a daunting challenge in the treatment of breast cancer (BC). Exosomes,
as intercellular communicative vectors in the tumor microenvironment, play an important role …
as intercellular communicative vectors in the tumor microenvironment, play an important role …
Exosome-mediated transfer of cancer cell resistance to antiestrogen drugs
Exosomes are small vesicles which are produced by the cells and released into the
surrounding space. They can transfer biomolecules into recipient cells. The main goal of the …
surrounding space. They can transfer biomolecules into recipient cells. The main goal of the …
The emerging role of extracellular vesicles in endocrine resistant breast cancer
G La Camera, L Gelsomino, A Caruso, S Panza… - Cancers, 2021 - mdpi.com
Simple Summary Two-thirds of breast cancer patients present an estrogen receptor–positive
tumor at diagnosis, and the main treatment options for these patients are endocrine …
tumor at diagnosis, and the main treatment options for these patients are endocrine …
[HTML][HTML] Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer cells
YY Shchegolev, DV Sorokin, AM Scherbakov… - BioImpacts …, 2023 - ncbi.nlm.nih.gov
Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer
cells - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …
cells - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …
Tumor malignancy by genetic transfer between cells forming cell-in-cell structures
R Wang, H Zhong, C Wang, X Huang, A Huang… - Cell Death & …, 2023 - nature.com
Cell-in-cell structures (CICs) refer to a type of unique structure with one or more cells within
another one, whose biological outcomes are poorly understood. The present study aims to …
another one, whose biological outcomes are poorly understood. The present study aims to …
Proteomic profiling of extracellular vesicles released by leptin-treated breast cancer cells: a potential role in cancer metabolism
L Gelsomino, I Barone, A Caruso, F Giordano… - International Journal of …, 2022 - mdpi.com
Tumor extracellular vesicles (EVs), as endocytic vesicles able to transport nucleic acids,
proteins, and metabolites in recipient cells, have been recognized fundamental mediators of …
proteins, and metabolites in recipient cells, have been recognized fundamental mediators of …
Multi-targeted effects of G4-aptamers and their antiproliferative activity against cancer cells
AM Ogloblina, AN Khristich, NY Karpechenko… - Biochimie, 2018 - Elsevier
We selected and investigated nine G-quadruplex (G4)-forming aptamers originally designed
against different proteins involved in the regulation of cellular proliferation (STAT3 …
against different proteins involved in the regulation of cellular proliferation (STAT3 …
[HTML][HTML] Irreversible inhibition of estrogen receptor α signaling and the emergence of hormonal resistance in MCF7 breast cancer cells induced by DNA damage …
AM Scherbakov, DV Sorokin… - Biomedical …, 2024 - … .spandidos-publications.com
Combining chemotherapy and hormone therapy is a prevalent approach in breast cancer
treatment. While the cytotoxic impact of numerous chemotherapy drugs stems from DNA …
treatment. While the cytotoxic impact of numerous chemotherapy drugs stems from DNA …
[HTML][HTML] Mechanisms underlying the increased chemosensitivity of bortezomib-resistant multiple myeloma by silencing nuclear transcription factor Snail1
Z Huang, X Liang, W Wu, X Chen… - Oncology …, 2019 - spandidos-publications.com
The Snail family transcriptional repressor 1 gene (Snail1) was screened in multiple myeloma
cells (MMCs) from bortezomib-resistant MM patients and was found to be significantly …
cells (MMCs) from bortezomib-resistant MM patients and was found to be significantly …
[HTML][HTML] Tamoxifen induces stem-like phenotypes and multidrug resistance by altering epigenetic regulators in ERα+ breast cancer cells
A Kalyanaraman… - Stem Cell …, 2020 - ncbi.nlm.nih.gov
Background To understand the mechanism underlying tamoxifen-induced multidrug
resistance (MDR) and stem-like phenotypes in breast cancer cells, we treated the MCF-7 …
resistance (MDR) and stem-like phenotypes in breast cancer cells, we treated the MCF-7 …