Exosomes and breast cancer drug resistance

X Dong, X Bai, J Ni, H Zhang, W Duan, P Graham… - Cell death & …, 2020 - nature.com
Drug resistance is a daunting challenge in the treatment of breast cancer (BC). Exosomes,
as intercellular communicative vectors in the tumor microenvironment, play an important role …

Exosome-mediated transfer of cancer cell resistance to antiestrogen drugs

SE Semina, AM Scherbakov, AA Vnukova, DV Bagrov… - Molecules, 2018 - mdpi.com
Exosomes are small vesicles which are produced by the cells and released into the
surrounding space. They can transfer biomolecules into recipient cells. The main goal of the …

The emerging role of extracellular vesicles in endocrine resistant breast cancer

G La Camera, L Gelsomino, A Caruso, S Panza… - Cancers, 2021 - mdpi.com
Simple Summary Two-thirds of breast cancer patients present an estrogen receptor–positive
tumor at diagnosis, and the main treatment options for these patients are endocrine …

[HTML][HTML] Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer cells

YY Shchegolev, DV Sorokin, AM Scherbakov… - BioImpacts …, 2023 - ncbi.nlm.nih.gov
Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer
cells - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Tumor malignancy by genetic transfer between cells forming cell-in-cell structures

R Wang, H Zhong, C Wang, X Huang, A Huang… - Cell Death & …, 2023 - nature.com
Cell-in-cell structures (CICs) refer to a type of unique structure with one or more cells within
another one, whose biological outcomes are poorly understood. The present study aims to …

Proteomic profiling of extracellular vesicles released by leptin-treated breast cancer cells: a potential role in cancer metabolism

L Gelsomino, I Barone, A Caruso, F Giordano… - International Journal of …, 2022 - mdpi.com
Tumor extracellular vesicles (EVs), as endocytic vesicles able to transport nucleic acids,
proteins, and metabolites in recipient cells, have been recognized fundamental mediators of …

Multi-targeted effects of G4-aptamers and their antiproliferative activity against cancer cells

AM Ogloblina, AN Khristich, NY Karpechenko… - Biochimie, 2018 - Elsevier
We selected and investigated nine G-quadruplex (G4)-forming aptamers originally designed
against different proteins involved in the regulation of cellular proliferation (STAT3 …

[HTML][HTML] Irreversible inhibition of estrogen receptor α signaling and the emergence of hormonal resistance in MCF7 breast cancer cells induced by DNA damage …

AM Scherbakov, DV Sorokin… - Biomedical …, 2024 - … .spandidos-publications.com
Combining chemotherapy and hormone therapy is a prevalent approach in breast cancer
treatment. While the cytotoxic impact of numerous chemotherapy drugs stems from DNA …

[HTML][HTML] Mechanisms underlying the increased chemosensitivity of bortezomib-resistant multiple myeloma by silencing nuclear transcription factor Snail1

Z Huang, X Liang, W Wu, X Chen… - Oncology …, 2019 - spandidos-publications.com
The Snail family transcriptional repressor 1 gene (Snail1) was screened in multiple myeloma
cells (MMCs) from bortezomib-resistant MM patients and was found to be significantly …

[HTML][HTML] Tamoxifen induces stem-like phenotypes and multidrug resistance by altering epigenetic regulators in ERα+ breast cancer cells

A Kalyanaraman… - Stem Cell …, 2020 - ncbi.nlm.nih.gov
Background To understand the mechanism underlying tamoxifen-induced multidrug
resistance (MDR) and stem-like phenotypes in breast cancer cells, we treated the MCF-7 …