Sleep has a homeostatic role in the regulation of the immune system and serves to constrain
activation of inflammatory signalling and expression of cellular inflammation. In patients with …

Purpose The aim of this “Year in Review” article is to summarize and discuss the
implications of biochemical marker related articles published between the Osteoarthritis …

Chronic pain patients often suffer from insomnia or impaired sleep which has been
associated with increased pain sensitivity, but a limited amount of studies have investigated …

Osteoarthritis (OA) is a leading cause of disability worldwide and clinical pain is the major
symptom of OA. This clinical OA-related pain is firmly associated with symptoms of insomnia …

Osteoarthritis (OA), a leading cause of disability and pain, affects 32.5 million Americans,
producing tremendous economic burden. Although some findings suggest that racial/ethnic …

Osteoarthritis (OA) is a leading cause of chronic pain and disability in older adults, which
most commonly affects the joints of the knee, hip, and hand. To date, there are no …

Abstract Study Objectives Females demonstrate heightened central sensitization (CS), a risk
factor for chronic pain characterized by enhanced responsivity of central nervous system …

A rapidly expanding scientific literature supports the frequent co-occurrence of sleep and
circadian disturbances following mild traumatic brain injury (mTBI). Although many …

Background Sleep disturbance is thought to aggravate acute postoperative pain. The
influence of preoperative sleep problems on pain control in the long‐term and development …

Importance Total knee arthroplasty (TKA) is one of the most common elective procedures
performed in adults with end-stage arthritis. Racial disparities in TKA outcomes have been …