The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …

The early, preclinical stages of bovine TB can be detected in live animals by the use of tests
of cellular immunity (the skin, γ-interferon and lymphocyte transformation tests). Tests of …

Leishmaniases remain a major public health problem today despite the vast amount of
research conducted on Leishmania pathogens. The biological model is genetically and …

Mycobacterium bovis is the cause of tuberculosis in cattle and is a member of the
Mycobacterium tuberculosis complex. In contrast to many other pathogenic bacterial …

The mycobacterial PE/PPE proteins have attracted much interest since their formal
identification just over a decade ago. It has been widely speculated that these proteins may …

The 6kDa early secreted antigenic target from Mycobacterium tuberculosis, ESAT-6, is the
prototype of a novel family of small proteins of unknown function produced by …

Bovine tuberculosis remains a major economic and animal welfare concern worldwide.
Cattle vaccination is being considered as part of control strategies. This approach, used …

The purified protein derivative (PPD) skin test for Mycobacterium tuberculosis infection lacks
specificity. We assessed 2 more specific M. tuberculosis antigens (ESAT-6 and CFP-10) by …

The currently used method for immunological detection of tuberculosis infection, the
tuberculin skin test, has low specificity. Antigens specific for Mycobacterium tuberculosis to …

Background Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), infects~ 8
million annually culminating in~ 2 million deaths. Moreover, about one third of the …