Large-scale genome-wide association studies conducted over the last decade have
uncovered numerous genetic variants associated with cardiometabolic traits and risk factors …

In this narrative review, we present data gathered over four decades (1980–2020) on the
epidemiology, pathophysiology and genetics of primary hyperparathyroidism (PHPT). PHPT …

Bone mineral density (BMD) assessed by DXA is used to evaluate bone health. In children,
total body (TB) measurements are commonly used; in older individuals, BMD at the lumbar …

Objectives To identify the genetic determinants of fracture risk and assess the role of 15
clinical risk factors on osteoporotic fracture risk. Design Meta-analysis of genome wide …

Background: DNA methylation is implicated in coronary heart disease (CHD), but current
evidence is based on small, cross-sectional studies. We examined blood DNA methylation …

Background Micronutrients, namely vitamins and minerals, are associated with cancer
outcomes; however, their reported effects have been inconsistent across studies. We aimed …

Background Micronutrients play an essential role at every stage of the immune response,
and deficiencies can therefore lead to increased susceptibility to infections. Previous …

Importance Serum calcium has been associated with cardiovascular disease in
observational studies and evidence from randomized clinical trials indicates that calcium …

The question of whether variable risk factors and various nutrients are causally related to
inflammatory bowel diseases (IBDs) has remained unanswered so far. Thus, this study …

Background Evidence for antioxidants, minerals and vitamins in relation to the risk of
Crohn's disease (CD) and ulcerative colitis (UC) is limited and inconsistent. This mendelian …