Machine learning-based models for prediction of toxicity outcomes in radiotherapy

LJ Isaksson, M Pepa, M Zaffaroni, G Marvaso… - Frontiers in …, 2020 - frontiersin.org
In order to limit radiotherapy (RT)-related side effects, effective toxicity prediction and
assessment schemes are essential. In recent years, the growing interest toward artificial …

Review and recommendations on deformable image registration uncertainties for radiotherapy applications

L Nenoff, F Amstutz, M Murr… - Physics in Medicine …, 2023 - iopscience.iop.org
Deformable image registration (DIR) is a versatile tool used in many applications in
radiotherapy (RT). DIR algorithms have been implemented in many commercial treatment …

[HTML][HTML] Artificial intelligence to predict outcomes of head and neck radiotherapy

C Bang, G Bernard, WT Le, A Lalonde… - Clinical and …, 2023 - Elsevier
Head and neck radiotherapy induces important toxicity, and its efficacy and tolerance vary
widely across patients. Advancements in radiotherapy delivery techniques, along with the …

Normal tissue complication probability (NTCP) models for modern radiation therapy

G Palma, S Monti, M Conson, R Pacelli, L Cella - Seminars in oncology, 2019 - Elsevier
Mathematical models of normal tissue complication probability (NTCP) able to robustly
predict radiation-induced morbidities (RIM) play an essential role in the identification of a …

Voxel-based analysis in radiation oncology: A methodological cookbook

G Palma, S Monti, L Cella - Physica Medica, 2020 - Elsevier
Recently, 2D or 3D methods for dose distribution analysis have been proposed as
evolutions of the Dose Volume Histogram (DVH) approaches. Those methods, collectively …

On the interplay between dosiomics and genomics in radiation-induced lymphopenia of lung cancer patients

S Monti, T Xu, Z Liao, R Mohan, L Cella… - Radiotherapy and …, 2022 - Elsevier
Purpose To investigate the interplay between spatial dose patterns and single nucleotide
polymorphisms in the development of radiation-induced lymphopenia (RIL) in 186 non-small …

[HTML][HTML] Risk of ischaemic cerebrovascular events in head and neck cancer patients is associated with carotid artery radiation dose

ESM van Aken, HP van der Laan, HP Bijl… - Radiotherapy and …, 2021 - Elsevier
Background and purpose Radiotherapy in the head and neck area may cause vascular
damage to the carotid arteries, increasing the risk of anterior circulation ischaemic …

[HTML][HTML] Normal Tissue Complication Probability (NTCP) prediction model for osteoradionecrosis of the mandible in patients with head and neck cancer after radiation …

LV van Dijk, AA Abusaif, J Rigert, MA Naser… - International Journal of …, 2021 - Elsevier
Purpose Osteoradionecrosis (ORN) of the mandible represents a severe, debilitating
complication of radiation therapy (RT) for head and neck cancer (HNC). At present, no …

A predictive nomogram for trismus after radiotherapy for head and neck cancer

M Massaccesi, N Dinapoli, V Fuga, C Rupe… - Radiotherapy and …, 2022 - Elsevier
Background The aim of this study is to develop a prediction model for trismus (maximal
interincisal distance equal to or less than 35 mm) based on a multivariable analysis of …

Spatial dose patterns associated with radiation pneumonitis in a randomized trial comparing intensity-modulated photon therapy with passive scattering proton …

G Palma, S Monti, T Xu, E Scifoni, P Yang… - International Journal of …, 2019 - Elsevier
Purpose Radiation pneumonitis (RP) is commonly associated with thoracic radiation
therapy, and its incidence is related to dose and volume of the normal lung in the path of …