Omentin is a recently identified adipose tissue-derived cytokine and is implicated in obesity-
related cardiovascular disorders. In the present study, we tested the hypothesis that omentin …

Abstract Background and Aim: Pioglitazone has diverse multiple effects on metabolic and
inflammatory processes that have the potential to influence cardiovascular disease …

Blood chemerin concentration shows positive correlation not only with body mass index and
serum triglyceride level but also with systolic blood pressure. While it seems likely that …

Visfatin is a novel adipocyte-derived cytokine. We hypothesized that visfatin could directly
affect vascular reactivity. To test the hypothesis, effects of visfatin on contraction of isolated …

Animal models of Alzheimer's disease (AD) are invaluable in dissecting the pathogenic
mechanisms and assessing the efficacy of potential new therapies. Here, we used the …

Pulmonary arterial (PA) hypertension (PAH) is a progressive and lethal disease that is
caused by increased vascular contractile reactivity and structural remodeling. These …

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear
transcription factors that regulate peripheral lipid and glucose metabolism. Three subtypes …

Increasing amounts of evidence implicate oxidative stress as having a pivotal role in age-
related cerebrovascular dysfunction, which is an important risk factor for the development of …

Background Type 2 diabetes mellitus (T2DM) is commonly associated with both
microvascular and macrovascular complications and a strong correlation exists between …

Purpose.: Pioglitazone, a peroxisome proliferator–activated receptor (PPAR)-γ agonist, has
anti-inflammatory and atheroprotective effects on vascular tissue and may reduce …