This Perspective examines the status of large-scale cortical interfaces through the lens of
potential applications to active implants for brain-machine interfaces. Examples of research …

Recording from a large neuronal population of neurons is a crucial challenge to unravel how
information is processed by the brain. In this review, we highlight the recent advances made …

Brain-machine interfaces hold promise for the restoration of sensory and motor function and
the treatment of neurological disorders, but clinical brain-machine interfaces have not yet …

Much development has been directed toward improving the performance and automation of
spike sorting. This continuous development, while essential, has contributed to an over …

This study presents a novel approach to improve the performance of microelectrode arrays
(MEAs) used for electrophysiological studies of neuronal networks. The integration of 3D …

The analysis of biomedical signals for clinical studies and therapeutic applications can
benefit from embedded devices that can process these signals locally and in real-time. An …

The ability to amplify, translate, and process small ionic potential fluctuations of neural
processes directly at the recording site is essential to improve the performance of neural …

This report describes a 3D microelectrode array integrated on a thin-film flexible cable for
neural recording in small animals. The fabrication process combines traditional silicon thin …

The efficacy of wireless intracortical brain–computer interfaces (iBCIs) is limited in part by
the number of recording channels, which is constrained by the power budget of the …

This article presents a recording front end for high-density CMOS neuronal probes with in
situ digitization and electrode offset voltage compensation. The analog front end (AFE) is …