Dendritic spine pathology: cause or consequence of neurological disorders?

JC Fiala, J Spacek, KM Harris - Brain research reviews, 2002 - Elsevier
Altered dendritic spines are characteristic of traumatized or diseased brain. Two general
categories of spine pathology can be distinguished: pathologies of distribution and …

Neuropathological changes caused by hydrocephalus

MR Del Bigio - Acta neuropathologica, 1993 - Springer
The medical literature concerning neuropathological changes caused by hydrocephalus is
reviewed. In both humans and experimental animals the ependyma suffers focal destruction …

Neuropathology and structural changes in hydrocephalus

MR Del Bigio - Developmental disabilities research reviews, 2010 - Wiley Online Library
In the context of spina bifida, hydrocephalus is usually caused by crowding of the posterior
fossa with obstruction to cerebrospinal fluid flow from the forth ventricle, and less often by …

Evidence that oxidative stress is associated with the pathophysiology of inherited hydrocephalus in the H-Tx rat model

DJ Socci, KB Bjugstad, HC Jones, JV Pattisapu… - Experimental …, 1999 - Elsevier
Oxidative stress can contribute to many neurological disease processes. Because many
events known to involve oxidative stress (infection, hemorrhage, brain trauma) are …

Brain damage in neonatal rats following kaolin induction of hydrocephalus

OH Khan, TL Enno, MR Del Bigio - Experimental neurology, 2006 - Elsevier
Neonatal and congenital hydrocephalus are common problems in humans. Hydrocephalus
was induced in 1-day-old rats by injection of kaolin into the cisterna magna. At 7 and 21 …

Neonatal hydrocephalus: mechanisms and consequences

JP McAllister II, P Chovan - Neurosurgery clinics of North America, 1998 - Elsevier
Although hydrocephalus is a multifactorial disorder, the processes responsible for
neurologic impairment can be classified into primary and secondary mechanisms. Primary …

Priorities for hydrocephalus research: report from a National Institutes of Health–sponsored workshop

MA Williams, JP McAllister, ML Walker… - Journal of …, 2007 - thejns.org
Object Treatment for hydrocephalus has not advanced appreciably since the advent of
cerebrospinal fluid (CSF) shunts more than 50 years ago. Many questions remain that …

The relationship between ventricular dilatation, neuropathological and neurobehavioural changes in hydrocephalic rats

FE Olopade, MT Shokunbi, AL Sirén - Fluids and Barriers of the CNS, 2012 - Springer
Background The motor and cognitive deficits observed in hydrocephalus are thought to be
due to axonal damage within the periventricular white matter. This study was carried out to …

Changes in periventricular vasculature of rabbit brain following induction of hydrocephalus and after shunting

MR Del Bigio, JE Bruni - Journal of neurosurgery, 1988 - thejns.org
✓ Hydrocephalus was induced in rabbits by injection of silicone oil into the cisterna magna.
At 1 and 8 weeks postinjection the rabbits were either sacrificed or treated by cerebrospinal …

Pathophysiologic consequences of hydrocephalus

MR Del Bigio - Neurosurgery Clinics of North America, 2001 - Elsevier
Hydrocephalus-induced damage is dependent on the rate and magnitude of ventricular
dilatation, the proximity to the ventricle, and the developmental stage at which the …