Transient receptor potential (TRP) channels are multifunctional signalling molecules with
many roles in sensory perception and cellular physiology. Therefore, it is not surprising that …

Anecdotal evidence that cannabis preparations have medical benefits together with the
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …

Genomic instability is a primary cause and fundamental feature of human cancer. However,
all cancer cell genotypes generally translate into several common pathophysiological …

The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

The transient receptor potential cation channel subfamily V member 1 (TRPV1) is a
transmembrane protein that can be activated by various physical and chemical stimuli and is …

Among the many signalling lipids, endocannabinoids are increasingly recognized for their
important roles in neuronal and glial development. Recent experimental evidence suggests …

Cancer involves defects in the mechanisms underlying cell proliferation, death and
migration. Calcium ions are central to these phenomena, serving as major signalling agents …

Transient receptor potential vanilloid 1 (TRPV1) is a calcium-permeable ion channel best
known for its ability to be gated by the pungent constituent of red chili pepper, capsaicin, and …

Apoptosis, a type of genetically controlled cell death, is a fundamental cellular mechanism
utilized by multicellular organisms for disposal of cells that are no longer needed or …

Transient receptor potential (TRP) channels are one primary type of calcium (Ca 2+)
permeable channels, and those relevant transmembrane and intracellular TRP channels …