Dysfunctional mitochondrial quality control (MQC) is implicated in the pathogenesis of
Parkinson's disease (PD). The improper selection of mitochondria for mitophagy increases …

Oxidative stress and neuroinflammation are common bases for disease onset and
progression in many neurodegenerative diseases. In Parkinson disease, which is …

Cell senescence has been implicated in the pathology of Parkinson's disease (PD). Both
abnormal α-synuclein aggregation and iron deposition are suggested to be the triggers …

Astrocytes, as the most abundant glial cells in the central nervous system, are tightly
integrated into neural networks and participate in numerous aspects of brain physiology and …

Synucleinopathies are a group of progressive neurodegenerative diseases known for the
accumulation of insoluble aggregates containing the protein alpha-synuclein (aSyn) …

Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder
characterized by motor and non-motor disturbances as a result of a complex and not fully …

Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting
the body and mind of millions of people in the world. As PD progresses, bradykinesia …

Considerable evidence suggests that insulin resistance is closely linked to Parkinson's
disease (PD), leading to agents aiming at treating diabetes can be regarded as new …

Neurodegenerative diseases, such as Alzheimer's and Parkinson's, are characterized by
several pathological features, including selective neuronal loss, aggregation of specific …

Parkinson's disease (PD) is the most common movement disorder and the second most
prevalent neurodegenerative disease after Alzheimer's disease. Despite decades of …