Zebrafish larvae as a behavioral model in neuropharmacology
Zebrafish larvae show a clear and distinct pattern of swimming in response to light and dark
conditions, following the development of a swim bladder at 4 days post fertilization. This …
conditions, following the development of a swim bladder at 4 days post fertilization. This …
Zebrafish models in neuropsychopharmacology and CNS drug discovery
Despite the high prevalence of neuropsychiatric disorders, their aetiology and molecular
mechanisms remain poorly understood. The zebrafish (Danio rerio) is increasingly utilized …
mechanisms remain poorly understood. The zebrafish (Danio rerio) is increasingly utilized …
Evaluation of developmental toxicity, developmental neurotoxicity, and tissue dose in zebrafish exposed to GenX and other PFAS
S Gaballah, A Swank, JR Sobus… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Per-and polyfluoroalkyl substances (PFAS) are a diverse class of industrial
chemicals with widespread environmental occurrence. Exposure to long-chain PFAS is …
chemicals with widespread environmental occurrence. Exposure to long-chain PFAS is …
Enhanced uptake of BPA in the presence of nanoplastics can lead to neurotoxic effects in adult zebrafish
Plastic particles have been proven to be abundant in the aquatic environment, raising
concerns about their potential toxic effects. In the present study, we determined the …
concerns about their potential toxic effects. In the present study, we determined the …
The potential for adverse effects in fish exposed to antidepressants in the aquatic environment
SL Gould, MJ Winter, WHJ Norton… - … Science & Technology, 2021 - ACS Publications
Antidepressants are one of the most commonly prescribed pharmaceutical classes for the
treatment of psychiatric conditions. They act via modulation of brain monoaminergic …
treatment of psychiatric conditions. They act via modulation of brain monoaminergic …
Developmental neurotoxicity of triphenyl phosphate in zebrafish larvae
Triphenyl phosphate (TPhP), a typical organophosphate ester, is frequently detected in the
environment and biota samples. It has been implicated as a neurotoxin as its structure is …
environment and biota samples. It has been implicated as a neurotoxin as its structure is …
Bioconcentration and transfer of the organophorous flame retardant 1, 3-dichloro-2-propyl phosphate causes thyroid endocrine disruption and developmental …
Q Wang, NLS Lai, X Wang, Y Guo… - … science & technology, 2015 - ACS Publications
Organophosphate flame retardants are emerging environmental contaminants, although
knowledge of their health risks is limited. Here, thyroid hormone homeostasis and neuronal …
knowledge of their health risks is limited. Here, thyroid hormone homeostasis and neuronal …
Multiview behavior and neurotransmitter analysis of zebrafish dyskinesia induced by 6PPD and its metabolites
J Ji, J Huang, N Cao, X Hao, Y Wu, Y Ma, D An… - Science of The Total …, 2022 - Elsevier
The typical tire manufacturing additive 6PPD, its metabolites 6PPDQ and 4-Hydroxy should
be monitored because of their ubiquitous presence in the environment and the high toxicity …
be monitored because of their ubiquitous presence in the environment and the high toxicity …
Zebrafish as an animal model for drug discovery in Parkinson's disease and other movement disorders: a systematic review
RL Vaz, TF Outeiro, JJ Ferreira - Frontiers in neurology, 2018 - frontiersin.org
Movement disorders can be primarily divided into hypokinetic and hyperkinetic. Most of the
hypokinetic syndromes are associated with the neurodegenerative disorder Parkinson's …
hypokinetic syndromes are associated with the neurodegenerative disorder Parkinson's …
Effects of ibuprofen, diclofenac and paracetamol on hatch and motor behavior in developing zebrafish (Danio rerio)
L Xia, L Zheng, JL Zhou - Chemosphere, 2017 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) which are widely used as pain relief
medicines are causing increasing environmental concern due to their incomplete removal in …
medicines are causing increasing environmental concern due to their incomplete removal in …