Foundations of gastrointestinal-based drug delivery and future developments
JN Chu, G Traverso - Nature Reviews Gastroenterology & Hepatology, 2022 - nature.com
Gastrointestinal-based drug delivery is considered the preferred mode of drug
administration owing to its convenience for patients, which improves adherence. However …
administration owing to its convenience for patients, which improves adherence. However …
Novel nano-encapsulated probiotic agents: Encapsulate materials, delivery, and encapsulation systems
C Xu, Q Ban, W Wang, J Hou, Z Jiang - Journal of Controlled Release, 2022 - Elsevier
Gut microbes are closely associated with most human health. When ingested orally,
probiotics can effectively regulate the composition and quantity of human intestinal …
probiotics can effectively regulate the composition and quantity of human intestinal …
Magnetically steerable bacterial microrobots moving in 3D biological matrices for stimuli-responsive cargo delivery
Bacterial biohybrids, composed of self-propelling bacteria carrying micro/nanoscale
materials, can deliver their payload to specific regions under magnetic control, enabling …
materials, can deliver their payload to specific regions under magnetic control, enabling …
Modular-designed engineered bacteria for precision tumor immunotherapy via spatiotemporal manipulation by magnetic field
X Ma, X Liang, Y Li, Q Feng, K Cheng, N Ma… - Nature …, 2023 - nature.com
Micro-nano biorobots based on bacteria have demonstrated great potential for tumor
diagnosis and treatment. The bacterial gene expression and drug release should be …
diagnosis and treatment. The bacterial gene expression and drug release should be …
A programmable encapsulation system improves delivery of therapeutic bacteria in mice
Living bacteria therapies have been proposed as an alternative approach to treating a broad
array of cancers. In this study, we developed a genetically encoded microbial encapsulation …
array of cancers. In this study, we developed a genetically encoded microbial encapsulation …
Chemically and biologically engineered bacteria‐based delivery systems for emerging diagnosis and advanced therapy
Bacteria are one of the main groups of organisms, which dynamically and closely participate
in human health and disease development. With the integration of chemical biotechnology …
in human health and disease development. With the integration of chemical biotechnology …
Surface-modified bacteria: synthesis, functionalization and biomedical applications
S Lin, F Wu, Y Zhang, H Chen, H Guo… - Chemical Society …, 2023 - pubs.rsc.org
The past decade has witnessed a great leap forward in bacteria-based living agents,
including imageable probes, diagnostic reagents, and therapeutics, by virtue of their unique …
including imageable probes, diagnostic reagents, and therapeutics, by virtue of their unique …
Mucosal immunity–mediated modulation of the gut microbiome by oral delivery of probiotics into Peyer's patches
Methods capable of maintaining gut microbiota homeostasis to prevent bacterial
translocation and infection under external threats are critical for multiple facets of human …
translocation and infection under external threats are critical for multiple facets of human …
Decorated bacteria and the application in drug delivery
F Wu, J Liu - Advanced Drug Delivery Reviews, 2022 - Elsevier
The use of living bacteria either as therapeutic agents or drug carriers has shown great
potential in treating a multitude of intractable diseases. However, cells are often fragile to …
potential in treating a multitude of intractable diseases. However, cells are often fragile to …
Cell membrane-coated mimics: a methodological approach for fabrication, characterization for therapeutic applications, and challenges for clinical translation
Cell membrane-coated (CMC) mimics are micro/nanosystems that combine an isolated cell
membrane and a template of choice to mimic the functions of a cell. The design exploits its …
membrane and a template of choice to mimic the functions of a cell. The design exploits its …