Chemical and Pharmacological Research of the Plants in Genus Euphorbia

QW Shi, XH Su, H Kiyota - Chemical reviews, 2008 - ACS Publications
The genus Euphorbia is the largest in the spurge family, comprising more than 2000 species
(Figure 1). 1 Some species of the genus Euphorbia have been used as medicinal plants for …

Synthesis of chiral cyclopentenones

SP Simeonov, JPM Nunes, K Guerra… - Chemical …, 2016 - ACS Publications
The cyclopentenone unit is a very powerful synthon for the synthesis of a variety of bioactive
target molecules. This is due to the broad diversity of chemical modifications available for …

Attractive natural products with strained cyclopropane and/or cyclobutane ring systems

YY Fan, XH Gao, JM Yue - Science China Chemistry, 2016 - Springer
The strained cyclopropane and/or cyclobutane subunits occurred in many complex natural
products including terpenoids, steroids and alkaloids. Natural products with cyclopropane …

Diterpenes from European Euphorbia Species Serving as Prototypes for Natural‐Product‐Based Drug Discovery

A Vasas, D Rédei, D Csupor, J Molnár… - European journal of …, 2012 - Wiley Online Library
Diterpenes occurring in plants of the Euphorbiaceae family are of considerable interest in
the context of natural product drug discovery programs because of their wide range of …

Anti-inflammatory Lathyrane Diterpenoids from Euphorbia lathyris

CY Zhang, YL Wu, P Zhang, ZZ Chen… - Journal of natural …, 2019 - ACS Publications
Six new lathyrane diterpenoids (1–6) and 10 known analogues (7–16), were separated from
the seeds of Euphorbia lathyris. The absolute configuration of 1 was determined by X-ray …

Drug affinity responsive target stability (DARTS) identifies laurifolioside as a new clathrin heavy chain modulator

F Dal Piaz, MB Vera Saltos… - Journal of natural …, 2016 - ACS Publications
Five new diterpenes (1–5) and a megastigmane derivative (6) were isolated from the aerial
parts of Euphorbia laurifolia, along with several known compounds. Their structures were …

Biologically active diterpenes containing a gem-dimethylcyclopropane subunit: an intriguing source of PKC modulators

MJ Durán-Peña, JMB Ares, IG Collado… - Natural product …, 2014 - pubs.rsc.org
Covering: 1973 to 2013 The biological activities of tigliane, lathyrane, ingenane, casbane,
jatropholane and premyrsinane diterpenoids which contain the gem-dimethylcyclopropyl …

Lathyrane-type diterpenoids from the seeds of Euphorbia lathyris

J Lu, G Li, J Huang, C Zhang, L Zhang, K Zhang, P Li… - Phytochemistry, 2014 - Elsevier
Ten lathyrane-type diterpenoids named Euphorbia Factor L 12–L 21 (1–10) and twelve
known diterpenoids (11–22) were isolated from seeds of Euphorbia lathyris. The structures …

Antitumor Effect of the Ethanolic Extract from Seeds of Euphorbia lathyris in Colorectal Cancer

C Mesas, R Martínez, R Ortíz, M Galisteo… - Nutrients, 2021 - mdpi.com
The seeds of Euphorbia lathyris have been used in traditional medicine to treat various
medical conditions. However, neither all of their active biocompounds nor the molecular …

Euphorikanin A, a Diterpenoid Lactone with a Fused 5/6/7/3 Ring System from Euphorbia kansui

DQ Fei, LL Dong, FM Qi, GX Fan, HH Li, ZY Li… - Organic …, 2016 - ACS Publications
Euphorikanin A (1), an unprecedented diterpenoid lactone which possesses a novel 5/6/7/3-
fused tetracyclic ring skeleton, was isolated from the roots of Euphorbia kansui. The …