Primary Toxoplasma gondii infection is usually subclinical, but cervical lymphadenopathy or
ocular disease can be present in some patients. Active infection is characterized by …

Toxoplasma gondii is a parasite that infects a wide range of animals and causes zoonotic
infections in humans. Although it normally only results in mild illness in healthy individuals …

Early electron microscopy studies revealed the elaborate cellular features that define the
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …

Key features: Written by the scientist who named this parasite and was the first to set up
proper diagnostic techniques Serves as the first ever book to provide information on the …

Despite being a frequent cause of severe diarrheal disease in infants and an opportunistic
infection in immunocompromised patients, Cryptosporidium research has lagged due to a …

Parasites and their hosts are engaged in reciprocal coevolution that balances competing
mechanisms of virulence, resistance, and evasion. This often leads to host specificity, but …

Efficient and site-specific alteration of the genome is key to decoding and altering the
genomic information of an organism. Over the last couple of years, the RNA-guided Cas9 …

Toxoplasma gondii evades host immunity to establish a chronic infection. Here, we
assessed the role of parasitophorous vacuole (PV) membrane (PVM)-and intravacuolar …

Apicomplexan parasites rely on cyclic nucleotide-dependent kinases for host cell infection,
yet the mechanisms that control their activation remain unknown. Here we show that an …

Toxoplasma gondii, a major zoonotic pathogen, possess a significant genetic and
phenotypic diversity that have been proposed to be responsible for the variation in clinical …