Gut microbiota and short chain fatty acids: implications in glucose homeostasis
Gut microbiota encompasses a wide variety of commensal microorganisms consisting of
trillions of bacteria, fungi, and viruses. This microbial population coexists in symbiosis with …
trillions of bacteria, fungi, and viruses. This microbial population coexists in symbiosis with …
Intestinal barrier and permeability in health, obesity and NAFLD
The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …
Oxygen battle in the gut: Hypoxia and hypoxia-inducible factors in metabolic and inflammatory responses in the intestine
The gastrointestinal tract is a highly proliferative and regenerative tissue. The intestine also
harbors a large and diverse microbial population collectively called the gut microbiome …
harbors a large and diverse microbial population collectively called the gut microbiome …
Regulation of immune cell function by short‐chain fatty acids
Short‐chain fatty acids (SCFAs) are bacterial fermentation products, which are chemically
composed by a carboxylic acid moiety and a small hydrocarbon chain. Among them, acetic …
composed by a carboxylic acid moiety and a small hydrocarbon chain. Among them, acetic …
Microbial-derived butyrate promotes epithelial barrier function through IL-10 receptor–dependent repression of claudin-2
L Zheng, CJ Kelly, KD Battista, R Schaefer… - The Journal of …, 2017 - journals.aai.org
Commensal interactions between the enteric microbiota and distal intestine play important
roles in regulating human health. Short-chain fatty acids (SCFAs), such as butyrate …
roles in regulating human health. Short-chain fatty acids (SCFAs), such as butyrate …
Intestinal epithelial claudins: expression and regulation in homeostasis and inflammation
V Garcia‐Hernandez, M Quiros… - Annals of the New York …, 2017 - Wiley Online Library
The intestinal epithelium forms a highly dynamic and selective barrier that controls
absorption of fluid and solutes while restricting pathogen access to underlying tissues …
absorption of fluid and solutes while restricting pathogen access to underlying tissues …
Intestinal permeability, inflammation and the role of nutrients
R Farré, M Fiorani, S Abdu Rahiman, G Matteoli - Nutrients, 2020 - mdpi.com
The interaction between host and external environment mainly occurs in the gastrointestinal
tract, where the mucosal barrier has a critical role in many physiologic functions ranging …
tract, where the mucosal barrier has a critical role in many physiologic functions ranging …
[HTML][HTML] Personalized redox medicine in inflammatory bowel diseases: an emerging role for HIF-1α and NRF2 as therapeutic targets
AR Bourgonje, D Kloska, A Grochot-Przęczek… - Redox Biology, 2023 - Elsevier
Inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative
colitis (UC), are intimately associated with inflammation and overproduction of reactive …
colitis (UC), are intimately associated with inflammation and overproduction of reactive …
Physiologic hypoxia and oxygen homeostasis in the healthy intestine. A review in the theme: cellular responses to hypoxia
In recent years, the intestinal mucosa has proven to be an intriguing organ to study tissue
oxygenation. The highly vascularized lamina propria juxtaposed to an anaerobic lumen …
oxygenation. The highly vascularized lamina propria juxtaposed to an anaerobic lumen …
Effects of dietary components on intestinal permeability in health and disease
K Khoshbin, M Camilleri - American Journal of Physiology …, 2020 - journals.physiology.org
Altered intestinal permeability plays a role in many pathological conditions. Intestinal
permeability is a component of the intestinal barrier. This barrier is a dynamic interface …
permeability is a component of the intestinal barrier. This barrier is a dynamic interface …