Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets
B Wang, L Wu, J Chen, L Dong, C Chen… - Signal transduction and …, 2021 - nature.com
The arachidonic acid (AA) pathway plays a key role in cardiovascular biology,
carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified …
carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified …
Prostaglandin E2 and cancer: insight into tumor progression and immunity
F Finetti, C Travelli, J Ercoli, G Colombo, E Buoso… - Biology, 2020 - mdpi.com
Simple Summary Inflammation is assessed as a hallmark of cancer and it is now widely
recognized that there exists a direct causal link between inflammation and tumors. Among …
recognized that there exists a direct causal link between inflammation and tumors. Among …
Ketogenic diet in cancer prevention and therapy: molecular targets and therapeutic opportunities
Although cancer is still one of the most significant global challenges facing public health, the
world still lacks complementary approaches that would significantly enhance the efficacy of …
world still lacks complementary approaches that would significantly enhance the efficacy of …
Immune regulatory processes of the tumor microenvironment under malignant conditions
K Pansy, B Uhl, J Krstic, M Szmyra, K Fechter… - International journal of …, 2021 - mdpi.com
The tumor microenvironment (TME) is a critical regulator of tumor growth, progression, and
metastasis. Since immune cells represent a large fraction of the TME, they play a key role in …
metastasis. Since immune cells represent a large fraction of the TME, they play a key role in …
Harnessing helminth-driven immunoregulation in the search for novel therapeutic modalities
Parasitic helminths have coevolved with humans over millennia, intricately refining and
developing an array of mechanisms to suppress or skew the host's immune system, thereby …
developing an array of mechanisms to suppress or skew the host's immune system, thereby …
[Retracted] Ferroptosis‐Related Long Noncoding RNAs as Prognostic Marker for Colon Adenocarcinoma
Y Qiu, H Li, Q Zhang, X Qiao… - Applied Bionics and …, 2022 - Wiley Online Library
Background. The incidence of colon adenocarcinoma (COAD) has been increasing over
time. Although ferroptosis and long noncoding RNAs (lncRNAs) have been extensively …
time. Although ferroptosis and long noncoding RNAs (lncRNAs) have been extensively …
Phospholipase A2 superfamily in cancer
Z Peng, Y Chang, J Fan, W Ji, C Su - Cancer Letters, 2021 - Elsevier
Phospholipase A2 enzymes (PLA 2 s) comprise a superfamily that is generally divided into
six subfamilies known as cytosolic PLA 2 s (cPLA 2 s), calcium-independent PLA 2 s (iPLA 2 …
six subfamilies known as cytosolic PLA 2 s (cPLA 2 s), calcium-independent PLA 2 s (iPLA 2 …
Cancer-associated fibroblasts derived extracellular vesicles promote angiogenesis of colorectal adenocarcinoma cells through miR-135b-5p/FOXO1 axis
X Dai, Y Xie, M Dong - Cancer Biology & Therapy, 2022 - Taylor & Francis
Colorectal adenocarcinoma (COAD) is a prevalent malignant tumor. Cancer-associated
fibroblasts (CAFs)-derived extracellular vesicles (EVs)(CAFs-EVs) are implicated in COAD …
fibroblasts (CAFs)-derived extracellular vesicles (EVs)(CAFs-EVs) are implicated in COAD …
The role of Th17 cells in the pathogenesis and treatment of breast cancer
V Karpisheh, M Ahmadi, K Abbaszadeh-Goudarzi… - Cancer Cell …, 2022 - Springer
Breast cancer is a severe problem worldwide due to an increase in mortality and prevalence
among women. Despite early diagnostic procedures as well as advanced therapies, more …
among women. Despite early diagnostic procedures as well as advanced therapies, more …
Reprogrammed lipid metabolism and the lipid-associated hallmarks of colorectal cancer
Simple Summary Colorectal cancer (CRC) is the third-most diagnosed cancer and the
second-leading cause of cancer-related deaths worldwide. Limitations in early and accurate …
second-leading cause of cancer-related deaths worldwide. Limitations in early and accurate …