Mesenchymal stem cells (MSCs) are promising seed cells for neural regeneration therapy
owing to their plasticity and accessibility. They possess several inherent characteristics …

A bone tissue engineering strategy involving the in vitro expansion of cells on a scaffold
before implantation into the body represents a promising alternative to current clinical …

Many diseases including cardiovascular disease, diabetes, osteoporosis, and cancers
cannot be treated effectively with current clinical therapy because of a significant reduction …

Bone is a hard-connective tissue composed of matrix, cells and bioactive factors with a
hierarchical structure, where the matrix is mainly composed of type I collagen and …

Gelatin has various attractive features as biomedical materials, for instance, biocompatibility,
low immunogenicity, biodegradability, and ease of manipulation. In recent years, various …

Regeneration of large bone defects is challenging in the next few years because the age of
the population is growing. Bone grafting as a gold standard of bone repairing is limited as a …

The objective of this study is to construct complex of DNA and PLGA/HAp composite scaffold
for bone tissue engineering. Naked DNA has low transfection efficiency so DNA loaded …

Almost 20 years after the invention of tissue engineering, autogenous bone grafting has
remained the favored strategy for the treatment of bone defects. As an alternative, a vast …

A new family of gene delivery vectors is synthesized consisting of a medium-size generation
PAMAM dendrimer (generation 5, with amine termini) core randomly linked at the periphery …

The development of biological methods over the past decade has stimulated great interest in
the possibility to regenerate human tissues. Advances in stem cell research, gene therapy …