[PDF][PDF] Motor unit
CJ Heckman, RM Enoka - Comprehensive physiology, 2012 - drive.google.com
Movement is accomplished by the controlled activation of motor unit populations. Our
understanding of motor unit physiology has been derived from experimental work on the …
understanding of motor unit physiology has been derived from experimental work on the …
A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade?
MC Bellingham - CNS neuroscience & therapeutics, 2011 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disease of
adults which preferentially attacks the neuromotor system. Riluzole has been used as the …
adults which preferentially attacks the neuromotor system. Riluzole has been used as the …
You are as fast as your motor neurons: speed of recruitment and maximal discharge of motor neurons determine the maximal rate of force development in humans
Key points We propose and validate a method for accurately identifying the activity of
populations of motor neurons during contractions at maximal rate of force development in …
populations of motor neurons during contractions at maximal rate of force development in …
Early functional impairment of sensory-motor connectivity in a mouse model of spinal muscular atrophy
To define alterations of neuronal connectivity that occur during motor neuron degeneration,
we characterized the function and structure of spinal circuitry in spinal muscular atrophy …
we characterized the function and structure of spinal circuitry in spinal muscular atrophy …
Single-layer graphene modulates neuronal communication and augments membrane ion currents
NP Pampaloni, M Lottner, M Giugliano… - Nature …, 2018 - nature.com
The use of graphene-based materials to engineer sophisticated biosensing interfaces that
can adapt to the central nervous system requires a detailed understanding of how such …
can adapt to the central nervous system requires a detailed understanding of how such …
Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells
Our understanding of the intrinsic mechanosensitive properties of human pluripotent stem
cells (hPSCs), in particular the effects that the physical microenvironment has on their …
cells (hPSCs), in particular the effects that the physical microenvironment has on their …
Spinal cholinergic interneurons regulate the excitability of motoneurons during locomotion
To effect movement, motoneurons must respond appropriately to motor commands. Their
responsiveness to these inputs, or excitability, is regulated by neuromodulators. Possible …
responsiveness to these inputs, or excitability, is regulated by neuromodulators. Possible …
Recovery of neuronal and network excitability after spinal cord injury and implications for spasticity
JM D'amico, EG Condliffe, KJB Martins… - Frontiers in integrative …, 2014 - frontiersin.org
The state of areflexia and muscle weakness that immediately follows a spinal cord injury
(SCI) is gradually replaced by the recovery of neuronal and network excitability, leading to …
(SCI) is gradually replaced by the recovery of neuronal and network excitability, leading to …
Adult spinal motoneurones are not hyperexcitable in a mouse model of inherited amyotrophic lateral sclerosis
N Delestrée, M Manuel, C Iglesias… - The Journal of …, 2014 - Wiley Online Library
Key points Intrinsic hyperexcitability of spinal motoneurones is thought to contribute to
excitotoxicity during amyotrophic lateral sclerosis (ALS), but it has never been demonstrated …
excitotoxicity during amyotrophic lateral sclerosis (ALS), but it has never been demonstrated …
Maximal discharge rate of motor units determines the maximal rate of force development during ballistic contractions in human
J Duchateau, S Baudry - Frontiers in human neuroscience, 2014 - frontiersin.org
The magnitude of the neural activation, and hence the force produced by a muscle, depend
on the number of motor units activated (recruitment) and the rates at which motor neurons …
on the number of motor units activated (recruitment) and the rates at which motor neurons …