Hemodynamic modeling, medical imaging, and machine learning and their applications to cardiovascular interventions

M Kadem, L Garber, M Abdelkhalek… - IEEE Reviews in …, 2022 - ieeexplore.ieee.org
Cardiovascular disease is a deadly global health crisis that carries a substantial financial
burden. Innovative treatment and management of cardiovascular disease straddles …

The critical role of lumped parameter models in patient-specific cardiovascular simulations

L Garber, S Khodaei, Z Keshavarz-Motamed - Archives of Computational …, 2022 - Springer
Cardiovascular (CV) disease impacts tens of millions of people annually and carries a
massive global economic burden. Continued advances in medical imaging, hardware and …

An ultrasound-exclusive non-invasive computational diagnostic framework for personalized cardiology of aortic valve stenosis

N Bahadormanesh, B Tomka, M Kadem… - Medical Image …, 2023 - Elsevier
Aortic stenosis (AS) is an acute and chronic cardiovascular disease and If left untreated,
50% of these patients will die within two years of developing symptoms. AS is characterized …

Personalized intervention cardiology with transcatheter aortic valve replacement made possible with a non-invasive monitoring and diagnostic framework

S Khodaei, A Henstock, R Sadeghi, S Sellers… - Scientific reports, 2021 - nature.com
One of the most common acute and chronic cardiovascular disease conditions is aortic
stenosis, a disease in which the aortic valve is damaged and can no longer function …

Coarctation of the aorta: diagnosis and management

S Raza, S Aggarwal, P Jenkins, A Kharabish, S Anwer… - Diagnostics, 2023 - mdpi.com
Coarctation of the aorta (CoA) accounts for approximately 5–8% of all congenital heart
defects. Depending on the severity of the CoA and the presence of associated cardiac …

Impact of extra-anatomical bypass on coarctation fluid dynamics using patient-specific lumped parameter and Lattice Boltzmann modeling

R Sadeghi, B Tomka, S Khodaei, MA Daeian… - Scientific Reports, 2022 - nature.com
Accurate hemodynamic analysis is not only crucial for successful diagnosis of coarctation of
the aorta (COA), but intervention decisions also rely on the hemodynamics assessment in …

Impact of mixed valvular disease on coarctation hemodynamics using patient-specific lumped parameter and Lattice Boltzmann modeling

R Sadeghi, N Gasner, S Khodaei, J Garcia… - International Journal of …, 2022 - Elsevier
The optimal course of intervention for patients with coexisting coarctation of the aorta (COA)
and mixed valvular disease (combinations of aortic and mitral valve pathologies, MVD) is an …

Reducing long‐term mortality post transcatheter aortic valve replacement requires systemic differentiation of patient‐specific coronary hemodynamics

S Khodaei, L Garber, M Abdelkhalek… - Journal of the …, 2023 - Am Heart Assoc
Background Despite the proven benefits of transcatheter aortic valve replacement (TAVR)
and its recent expansion toward the whole risk spectrum, coronary artery disease is present …

Long-term prognostic impact of paravalvular leakage on coronary artery disease requires patient-specific quantification of hemodynamics

S Khodaei, L Garber, J Bauer, A Emadi… - Scientific Reports, 2022 - nature.com
Transcatheter aortic valve replacement (TAVR) is a frequently used minimally invasive
intervention for patient with aortic stenosis across a broad risk spectrum. While coronary …

A diagnostic, monitoring, and predictive tool for patients with complex valvular, vascular and ventricular diseases

Z Keshavarz-Motamed - Scientific Reports, 2020 - nature.com
Hemodynamics quantification is critically useful for accurate and early diagnosis, but we still
lack proper diagnostic methods for many cardiovascular diseases. Furthermore, as most …