As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …

Periodontitis is an inflammatory disease caused by bacterial infection directly, and the
dysregulation of host immune-inflammatory response finally destroys periodontal tissues …

There is a growing interest in the complex role of host defense peptides (HDPs) in the
pathophysiology of several immune-mediated inflammatory diseases. The physicochemical …

Introduction: A biomarker is a biological indicator of normal or pathogenic processes.
Identification of biomarkers is useful for the prevention, diagnosis and prognosis of diseases …

The review aimed to investigate the diversity of oral microbiota and its influencing factors, as
well as the association of oral microbiota with oral health and the possible effects of …

Periodontal disease (PD), a chronic inflammatory disorder that damages the tooth and its
supporting components, is a common global oral health problem. Understanding the …

The recent epidemic caused by aerosolized SARS-CoV-2 virus illustrates the importance
and vulnerability of the mucosal epithelial barrier against infection. Antimicrobial proteins …

Neurodegenerative diseases (NDDs), such as Alzheimer's disease, Parkinson's disease,
and Huntington's disease, are disorders, which cause irreversible and progressive …

Health-care systems that develop rapidly and efficiently may increase the lifespan of
humans. Nevertheless, the older population is more fragile, and is at an increased risk of …

The impact of oral pathogens onto the generation and variability of oral tumors has only
recently been investigated. To get further insights, oral cancer cells were treated with …