The global H5N1 influenza panzootic in mammals

T Peacock, L Moncla, G Dudas, D VanInsberghe… - Nature, 2024 - nature.com
Influenza A viruses (IAV) have caused more documented global pandemics in human
history than any other pathogen1, 2. High pathogenicity avian influenza (HPAI) viruses …

Evolution, global spread, and pathogenicity of highly pathogenic avian influenza H5Nx clade 2.3. 4.4

DH Lee, K Bertran, JH Kwon… - Journal of veterinary …, 2017 - synapse.koreamed.org
Novel subtypes of Asian-origin (Goose/Guangdong lineage) H5 highly pathogenic avian
influenza (HPAI) viruses belonging to clade 2.3. 4, such as H5N2, H5N5, H5N6, and H5N8 …

The episodic resurgence of highly pathogenic avian influenza H5 virus

R Xie, KM Edwards, M Wille, X Wei, SS Wong, M Zanin… - Nature, 2023 - nature.com
Highly pathogenic avian influenza (HPAI) H5N1 activity has intensified globally since 2021,
increasingly causing mass mortality in wild birds and poultry and incidental infections in …

[HTML][HTML] Intercontinental movement of highly pathogenic avian influenza A (H5N1) clade 2.3. 4.4 virus to the United States, 2021

SN Bevins, SA Shriner, JC Cumbee Jr… - Emerging infectious …, 2022 - ncbi.nlm.nih.gov
We detected Eurasian-origin highly pathogenic avian influenza A (H5N1) virus belonging to
the Gs/GD lineage, clade 2.3. 4.4 b, in wild waterfowl in 2 Atlantic coastal states in the United …

[HTML][HTML] H5N1 highly pathogenic avian influenza clade 2.3. 4.4 b in wild and domestic birds: Introductions into the United States and reassortments, December 2021 …

S Youk, MK Torchetti, K Lantz, JB Lenoch, ML Killian… - Virology, 2023 - Elsevier
Highly pathogenic avian influenza viruses (HPAIVs) of the A/goose/Guangdong/1/1996
lineage H5 clade 2.3. 4.4 b continue to have a devastating effect on domestic and wild birds …

Characterization of neurotropic HPAI H5N1 viruses with novel genome constellations and mammalian adaptive mutations in free-living mesocarnivores in Canada

TN Alkie, S Cox, C Embury-Hyatt… - Emerging microbes & …, 2023 - Taylor & Francis
The GsGd lineage (A/goose/Guangdong/1/1996) H5N1 virus was introduced to Canada in
2021/2022 through the Atlantic and East Asia-Australasia/Pacific flyways by migratory birds …

Ecological divergence of wild birds drives avian influenza spillover and global spread

NJ Hill, MA Bishop, NS Trovão, KM Ineson… - PLoS …, 2022 - journals.plos.org
The diversity of influenza A viruses (IAV) is primarily hosted by two highly divergent avian
orders: Anseriformes (ducks, swans and geese) and Charadriiformes (gulls, terns and …

A brief history of bird flu

SJ Lycett, F Duchatel, P Digard - … Transactions of the …, 2019 - royalsocietypublishing.org
In 1918, a strain of influenza A virus caused a human pandemic resulting in the deaths of 50
million people. A century later, with the advent of sequencing technology and corresponding …

Role for migratory wild birds in the global spread of avian influenza H5N8

Global Consortium for H5N8 and Related Influenza … - Science, 2016 - science.org
Avian influenza viruses affect both poultry production and public health. A subtype H5N8
(clade 2.3. 4.4) virus, following an outbreak in poultry in South Korea in January 2014 …

Highly pathogenic avian influenza is an emerging disease threat to wild birds in North America

AM Ramey, NJ Hill, TJ DeLiberto… - The Journal of …, 2022 - Wiley Online Library
Prior to the emergence of the A/goose/Guangdong/1/1996 (Gs/GD) H5N1 influenza A virus,
the long‐held and well‐supported paradigm was that highly pathogenic avian influenza …