Accumulating knowledge on the biology and function of the adipose tissue has led to a
major shift in our understanding of its role in health and disease. The adipose tissue is now …

This review presents recent developments and a wide overview of broadband time domain
diffuse optical spectroscopy (TD-DOS). Various topics including physics of photon migration …

Fluorescent probes sensitive to microenvironments have constantly been attractive, due to
their significant benefits in monitoring changes in the pathophysiological microenvironment …

This work presents the design and validation of an instrument for dual-slope broadband
diffuse reflectance spectroscopy. This instrument affords calibration-free, continuous-wave …

Rationale: Prediabetes can be reversed through lifestyle intervention, but its main pathologic
hallmark, insulin resistance (IR), cannot be detected as conveniently as blood glucose …

The human abdominal region is very heterogeneous and stratified with subcutaneous
adipose tissue (SAT) being one of the primary layers. Monitoring this tissue is crucial for …

Frequency-domain near-infrared spectroscopy (FD-NIRS) provides quantitative noninvasive
measurements of tissue optical absorption and scattering, as well as a safe and accurate …

The goal of this study is to identify non-invasive optical hemodynamic biomarkers that can
index laboratory hematology measurements in sickle cell disease (SCD). We acquired …

RESULTS: Body weight, body fat percentage and adipocyte size decreased significantly
during the DI period. The DI markedly decreased AT pO 2 and improved insulin sensitivity …

We report a narrow wavelength band diffuse reflectance spectroscopy (nb-DRS) method to
determine water and fat ratios of scattering media in the 900–1000 nm range. This method …