Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Antimicrobial peptides: An alternative to traditional antibiotics

S Ji, F An, T Zhang, M Lou, J Guo, K Liu, Y Zhu… - European Journal of …, 2024 - Elsevier
As antibiotic-resistant bacteria and genes continue to emerge, the identification of effective
alternatives to traditional antibiotics has become a pressing issue. Antimicrobial peptides …

CAMPR4: a database of natural and synthetic antimicrobial peptides

U Gawde, S Chakraborty, FH Waghu… - Nucleic Acids …, 2023 - academic.oup.com
There has been an exponential increase in the design of synthetic antimicrobial peptides
(AMPs) for its use as novel antibiotics. Synthetic AMPs are substantially enriched in residues …

DBAASP v3: database of antimicrobial/cytotoxic activity and structure of peptides as a resource for development of new therapeutics

M Pirtskhalava, AA Amstrong, M Grigolava… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is an
open-access, comprehensive database containing information on amino acid sequences …

sAMPpred-GAT: prediction of antimicrobial peptide by graph attention network and predicted peptide structure

K Yan, H Lv, Y Guo, W Peng, B Liu - Bioinformatics, 2023 - academic.oup.com
Abstract Motivation Antimicrobial peptides (AMPs) are essential components of therapeutic
peptides for innate immunity. Researchers have developed several computational methods …

DRAMP 3.0: an enhanced comprehensive data repository of antimicrobial peptides

G Shi, X Kang, F Dong, Y Liu, N Zhu, Y Hu… - Nucleic acids …, 2022 - academic.oup.com
Stapled antimicrobial peptides are an emerging class of artificial cyclic peptide molecules
which have antimicrobial activity and potent structure stability. We previously published the …

Accelerating antibiotic discovery through artificial intelligence

MCR Melo, JRMA Maasch… - Communications …, 2021 - nature.com
By targeting invasive organisms, antibiotics insert themselves into the ancient struggle of the
host-pathogen evolutionary arms race. As pathogens evolve tactics for evading antibiotics …

dbAMP 2.0: updated resource for antimicrobial peptides with an enhanced scanning method for genomic and proteomic data

JH Jhong, L Yao, Y Pang, Z Li, CR Chung… - Nucleic acids …, 2022 - academic.oup.com
The last 18 months, or more, have seen a profound shift in our global experience, with many
of us navigating a once-in-100-year pandemic. To date, COVID-19 remains a life …

Strategic approaches to improvise peptide drugs as next generation therapeutics

P Barman, S Joshi, S Sharma, S Preet… - International journal of …, 2023 - Springer
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

Comprehensive assessment of machine learning-based methods for predicting antimicrobial peptides

J Xu, F Li, A Leier, D Xiang, HH Shen… - Briefings in …, 2021 - academic.oup.com
Antimicrobial peptides (AMPs) are a unique and diverse group of molecules that play a
crucial role in a myriad of biological processes and cellular functions. AMP-related studies …