Background The time course of blood lactate levels could be helpful to assess a patient's
response to therapy. Although the focus of published studies has been largely on septic …

Lactate levels are commonly evaluated in acutely ill patients. Although most often used in
the context of evaluating shock, lactate levels can be elevated for many reasons. While …

In patients with acute kidney injury (AKI), optimization of systemic haemodynamics is central
to the clinical management. However, considerable debate exists regarding the efficacy …

Objectives: Lactate clearance has been widely investigated for its prognostic value in
critically ill patients. However, the results are conflicting. The present study aimed to explore …

Serum lactate levels are traditionally interpreted as a marker of tissue hypoxia and often
used clinically as an indicator of severity and outcome of sepsis/septic shock. Interestingly …

Importance Improving emergency care of pediatric sepsis is a public health priority, but
optimal early diagnostic approaches are unclear. Measurement of lactate levels is …

Purpose To evaluate the prognostic value of the Cv-aCO 2/Da-vO 2 ratio combined with
lactate levels during the early phases of resuscitation in septic shock. Methods Prospective …

Background This study was design to investigate the prognostic value for death at day-28 of
lactate course and lactate clearance during the first 24 hours in Intensive Care Unit (ICU) …

Sepsis and septic shock are syndromes of immense clinical importance. Suspected sepsis
accounts for more than half a million emergency department visits annually in the United …

Over the last two decades, there have been vast improvements in sepsis-related outcomes,
largely resulting from the widespread adoption of aggressive fluid resuscitation and infection …