Genome-wide association studies on human behavioural traits are producing large amounts
of polygenic signals with significant predictive power and potentially useful biological clues …

Studying how genetic predispositions come together with environmental factors to contribute
to complex behavioral outcomes has great potential for advancing the understanding of the …

Approximately 70 percent of the mutations in cystic fibrosis patients correspond to a specific
deletion of three base pairs, which results in the loss of a phenylalanine residue at amino …

An understanding of the basic defect in the inherited disorder cystic fibrosis requires cloning
of the cystic fibrosis gene and definition of its protein product. In the absence of direct …

While originally characterized as a collection of related syndromes, cystic fibrosis (CF) is
now recognized as a single disease whose diverse symptoms stem from the wide tissue …

Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in
Medicine returns as one of the most favored texts in this fascinating and rapidly evolving …

X-linked Alport syndrome is a hereditary glomerulonephritis in which progressive loss of
kidney function is often accompanied by progressive loss of hearing. Ultrastructural defects …

Alzheimer's disease is a leading cause of morbidity and mortality among the elderly. Several
families have been described in which Alzheimer's disease is caused by an autosomal …

A large collection of good genetic markers is needed to map the genes that cause human
genetic diseases. Although nearly 400 polymorphic DNA markers for human chromosomes …

Cystic fibrosis (CF) is a common genetic disorder in the Caucasian population. The gene
was identified in 1989 on the basis of its map location on chromosome 7. The encoded gene …