Effects of chronic fluoxetine treatment on anxiety-and depressive-like behaviors in adolescent rodents–systematic review and meta-analysis
J Kryst, I Majcher-Maślanka, A Chocyk - Pharmacological Reports, 2022 - Springer
Background Drugs prescribed for psychiatric disorders in adolescence should be studied
very extensively since they can affect developing and thus highly plastic brain differently …
very extensively since they can affect developing and thus highly plastic brain differently …
Chlordiazepoxide reduces anxiety-like behavior in the adolescent mouse elevated plus maze: a pharmacological validation study
A Themann, M Rodriguez, J Reyes-Arce… - Pharmacology …, 2024 - Elsevier
This report evaluates the effects of chlordiazepoxide, a benzodiazepine commonly
prescribed to manage anxiety-related disorders in adolescent/pediatric populations, on …
prescribed to manage anxiety-related disorders in adolescent/pediatric populations, on …
[HTML][HTML] Sex-Specific Alterations in Spatial Memory and Hippocampal AKT-mTOR Signaling in Adult Mice Pre-exposed to Ketamine and/or Psychological Stress …
Background Ketamine (KET) is administered to manage major depression in adolescent
patients. However, the long-term effects of juvenile KET exposure on memory-related tasks …
patients. However, the long-term effects of juvenile KET exposure on memory-related tasks …
Acute and long‐lasting effects of adolescent fluoxetine exposure on feeding behavior in Sprague–Dawley rats
The antidepressant medication fluoxetine (FLX) is frequently prescribed for the management
of mood‐related illnesses in the adolescent population—yet its long‐term neurobehavioral …
of mood‐related illnesses in the adolescent population—yet its long‐term neurobehavioral …
Autophagy induction and accumulation of phosphorylated tau in the hippocampus and prefrontal cortex of adult C57BL/6 mice subjected to adolescent fluoxetine …
JA Sierra-Fonseca, M Rodriguez… - Journal of …, 2021 - content.iospress.com
Background: Fluoxetine (FLX) represents the antidepressant of choice for the management
of pediatric mood-related illnesses. Accumulating preclinical evidence suggests that …
of pediatric mood-related illnesses. Accumulating preclinical evidence suggests that …
Effect of early-life stress or fluoxetine exposure on later-life conditioned taste aversion learning in Sprague-Dawley rats
VA Gutierrez, AA Carrillo, GJ Boersma… - Neuroscience …, 2022 - Elsevier
In rodents, early-life exposure to environmental stress or antidepressant medication
treatment has been shown to induce similar long-term consequences on memory-and …
treatment has been shown to induce similar long-term consequences on memory-and …
Social defeat stress induces an anxiety-like outcome in male prairie voles (Microtus ochrogaster)
M Rodriguez, A Themann, DE Calvo… - Oxford Open …, 2024 - academic.oup.com
Anxiety-related illnesses constitute one of the leading causes of disability across the globe.
Consequently, the need for validated preclinical models to uncover the etiology of anxiety …
Consequently, the need for validated preclinical models to uncover the etiology of anxiety …
The Evolving Role of Animal Models in the Discovery and Development of Novel Treatments for Psychiatric Disorders
LB Teal, SM Ingram, M Bubser, E McClure… - Drug Development in …, 2023 - Springer
Historically, animal models have been routinely used in the characterization of novel
chemical entities (NCEs) for various psychiatric disorders. Animal models have been …
chemical entities (NCEs) for various psychiatric disorders. Animal models have been …
Adolescent fluoxetine exposure increases ERK-related signaling within the prefrontal cortex of adult male Sprague-Dawley rats
A Themann, M Rodriguez… - Oxford open …, 2022 - academic.oup.com
There has been a disproportionate increase in fluoxetine (FLX) prescription rates within the
juvenile population. Thus, we evaluated how adolescent FLX exposure alters expression …
juvenile population. Thus, we evaluated how adolescent FLX exposure alters expression …
Sex-dependent effects of pair bond interruption on anxiety-and depression-like behaviors in adult mandarin voles
Y Feng, Y Yang, Y Wang, X Lv, X Zhang, Y Wang… - Behavioural …, 2021 - Elsevier
Stable and positive social bonds are pretty vital to the development of animals. Instability
and disruptions of social bonds, such as maternal separation and social isolation, always …
and disruptions of social bonds, such as maternal separation and social isolation, always …