Early-onset neonatal sepsis

KA Simonsen, AL Anderson-Berry… - Clinical microbiology …, 2014 - Am Soc Microbiol
Early-onset sepsis remains a common and serious problem for neonates, especially preterm
infants. Group B streptococcus (GBS) is the most common etiologic agent, while Escherichia …

Management of neonates born at≤ 34 6/7 weeks' gestation with suspected or proven early-onset bacterial sepsis

KM Puopolo, WE Benitz, TE Zaoutis, J Cummings… - …, 2018 - publications.aap.org
Early-onset sepsis (EOS) remains a serious and often fatal illness among infants born
preterm, particularly among newborn infants of the lowest gestational age. Currently, most …

Early-onset neonatal sepsis 2015 to 2017, the rise of Escherichia coli, and the need for novel prevention strategies

BJ Stoll, KM Puopolo, NI Hansen, PJ Sánchez… - JAMA …, 2020 - jamanetwork.com
Importance Early-onset sepsis (EOS) remains a potentially fatal newborn condition. Ongoing
surveillance is critical to optimize prevention and treatment strategies. Objective To describe …

[PDF][PDF] Mean platelet volume (MPV) may simply predict the severity of sepsis in preterm infants

C Tayman, A Tonbul, H Akca, M Bilici - Clin Lab, 2014 - academia.edu
Background: To evaluate the efficacy of serial mean platelet volume (MPV) measurements in
diagnosis and follow-up of sepsis and to compare its effectiveness with C-reactive protein …

Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18

JL Wynn, CS Wilson, J Hawiger… - Proceedings of the …, 2016 - National Acad Sciences
Interleukin (IL)-18 is an important effector of innate and adaptive immunity, but its expression
must also be tightly regulated because it can potentiate lethal systemic inflammation and …

Clinical and microbiologic characteristics of early-onset sepsis among very low birth weight infants: opportunities for antibiotic stewardship

S Mukhopadhyay, KM Puopolo - The Pediatric infectious disease …, 2017 - journals.lww.com
Background: Most very low birth weight (VLBW, birth weight< 1500 g) infants receive empiric
antibiotics for risk of early-onset sepsis (EOS). The objective of this study was to determine …

Neonatal sepsis: a continuing disease burden

M Satar, F Ozlü - The Turkish journal of pediatrics, 2012 - turkjpediatr.org
Sepsis-related morbidity and mortality are increasing concerns in all Neonatal Intensive
Care Units, with reported incidences that are dramatically high regardless of the …

Methicillin-Resistant and Susceptible Staphylococcus aureus Bacteremia and Meningitis in Preterm Infants

AL Shane, NI Hansen, BJ Stoll, EF Bell… - …, 2012 - publications.aap.org
BACKGROUND: Data are limited on the impact of methicillin-resistant Staphylococcus
aureus (MRSA) on morbidity and mortality among very low birth weight (VLBW) infants with …

Group B Streptococcus and Escherichia coli infections in the intensive care nursery in the era of intrapartum antibiotic prophylaxis

MS Bauserman, MM Laughon, CP Hornik… - The Pediatric …, 2013 - journals.lww.com
Background: Group B Streptococcus (GBS) and Escherichia coli cause serious bacterial
infections (SBIs) and are associated with morbidity and mortality in newborn infants …

The phenotype and function of preterm infant monocytes: implications for susceptibility to infection

E De Jong, T Strunk, D Burgner… - Journal of leukocyte …, 2017 - academic.oup.com
The extreme vulnerability of preterm infants to invasive microbial infections has been
attributed to “immature” innate immune defenses. Monocytes are important innate immune …