The critical roles of m6A RNA methylation in lung cancer: from mechanism to prognosis and therapy

MN Diao, XJ Zhang, YF Zhang - British Journal of Cancer, 2023 - nature.com
Lung cancer, a highly malignant disease, greatly affects patients' quality of life. N6-
methyladenosine (m6A) is one of the most common posttranscriptional modifications of …

[HTML][HTML] Construction of N-7 methylguanine-related mRNA prognostic model in uterine corpus endometrial carcinoma based on multi-omics data and immune-related …

J Zhao, J Zou, W Jiao, L Lin, J Wang, Z Lin - Scientific Reports, 2022 - nature.com
Abstract N-7 methylguanine (m7G) is one of the most common RNA base modifications in
post-transcriptional regulation, which participates in multiple processes such as …

[PDF][PDF] RNA modifications meet tumors

Z Yang, S Zhang, T Xia, Y Fan, Y Shan… - Cancer Management …, 2022 - Taylor & Francis
RNA modifications occur through the whole process of gene expression regulation,
including transcription, translation, and post-translational processes. They are closely …

[HTML][HTML] Immune-related gene signature associates with immune landscape and predicts prognosis accurately in patients with Wilms tumour

XM Tian, B Xiang, LM Jin, T Mi, JK Wang… - Frontiers in …, 2022 - frontiersin.org
Wilms tumour (WT) is the most common kidney malignancy in children. Chemoresistance is
the leading cause of tumour recurrence and poses a substantial therapeutic challenge …

[Retracted] Delicaflavone Represses Lung Cancer Growth by Activating Antitumor Immune Response through N6‐Methyladenosine Transferases and Oxidative …

X Wang, D Xu, B Chen, D Huang, Z Li… - Oxidative Medicine …, 2022 - Wiley Online Library
Our previous studies have shown that delicaflavone (DLL), a biocomponent extracted from
Selaginella doederleinii Hieron, has antitumor activity. However, the role of DLL in the …

[HTML][HTML] Significance of m6A regulatory factor in gene expression and immune function of osteoarthritis

X Xie, Y Zhang, J Yu, F Jiang, C Wu - Frontiers in Physiology, 2022 - frontiersin.org
One of the most prevalent posttranscriptional modifications of eukaryotic mRNA is the RNA
N6-methyladenosine (m6A) regulator, which plays a significant role in various illnesses. The …

[HTML][HTML] Comprehensive analysis for cellular senescence-related immunogenic characteristics and immunotherapy prediction of acute myeloid leukemia

Y Mao, J Xu, X Xu, J Qiu, Z Hu, F Jiang… - Frontiers in …, 2022 - frontiersin.org
In malignancies, cellular senescence is critical for carcinogenesis, development, and
immunological regulation. Patients with acute myeloid leukemia (AML) have not investigated …

[HTML][HTML] M7G methylated core genes (METTL1 and WDR4) and associated RNA risk signatures are associated with prognosis and immune escape in HCC

R Li, X Liu, K Deng, X Wang - BMC Medical Genomics, 2023 - Springer
Abstract N7 methylguanosine (m7G) has a crucial role the development of hepatocellular
carcinoma (HCC). This study aimed to investigate the impact of the m7G methylation core …

[HTML][HTML] Identification of necroptosis-related subtypes, development of a novel signature, and characterization of immune infiltration in colorectal cancer

M Sun, X Ji, M Xie, X Chen, B Zhang, X Luo… - Frontiers in …, 2022 - frontiersin.org
Introduction Necroptosis, a type of programmed cell death, has recently been extensively
studied as an important pathway regulating tumor development, metastasis, and immunity …

[HTML][HTML] Integrated Bioinformatics analysis identifies robust biomarkers and its correlation with immune Microenvironment in Nonalcoholic fatty liver disease

F Zhang, Z Zhang, Y Li, Y Sun, X Zhou, X Chen… - Frontiers in …, 2022 - frontiersin.org
Objective: Nonalcoholic fatty liver disease (NAFLD) is a serious threat to human health
worldwide. In this study, the aim is to analyze diagnosis biomarkers in NAFLD and its …