Arylglyoxals in synthesis of heterocyclic compounds

B Eftekhari-Sis, M Zirak, A Akbari - Chemical reviews, 2013 - ACS Publications
Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …

Regio‐and Chemoselective Metalation of Arenes and Heteroarenes Using Hindered Metal Amide Bases

B Haag, M Mosrin, H Ila, V Malakhov… - Angewandte Chemie …, 2011 - Wiley Online Library
The preparation of highly functionalized organometallic compounds can be achieved by
direct C H activation of a broad range of unsaturated substrates using lithium chloride …

Site-selective Suzuki–Miyaura coupling of heteroaryl halides–understanding the trends for pharmaceutically important classes

J Almond-Thynne, DC Blakemore, DC Pryde… - Chemical …, 2017 - pubs.rsc.org
Suzuki–Miyaura cross-coupling reactions of heteroaryl polyhalides with aryl boronates are
surveyed. Drawing on data from literature sources as well as bespoke searches of Pfizer's …

Luminescent materials incorporating pyrazine or quinoxaline moieties

S Achelle, C Baudequin, N Plé - Dyes and Pigments, 2013 - Elsevier
Though the past few decades, the development of new luminescent materials has received
a lot of attention due to their applications as fluorescent sensors, in biological microscopy …

Recent progress of isocyanide-based multicomponent reactions in Iran

A Shaabani, A Maleki, AH Rezayan, A Sarvary - Molecular diversity, 2011 - Springer
The aim of this review is to provide an overview of the contributions and recent advances
made by Iranian scientists in the field of isocyanide-based reactions between 1999 and …

Selective Palladium‐Catalyzed Suzuki–Miyaura Reactions of Polyhalogenated Heteroarenes

R Rossi, F Bellina, M Lessi - Advanced Synthesis & Catalysis, 2012 - Wiley Online Library
Abstract The palladium‐catalyzed Suzuki–Miyaura reaction of multiply halogenated,
electron‐rich and electron‐deficient heteroarenes is one of the most reliable and …

Synthesis of unsymmetrical pyrazines based on α-diazo oxime ethers

NSY Loy, S Kim, CM Park - Organic letters, 2015 - ACS Publications
Synthesis of unsymmetrically substituted pyrazines has been a challenge. The reactivity of α-
imino carbenoids derived from α-diazo oxime ethers has been exploited for pyrazine …

Iron-catalyzed cross-coupling of electron-deficient heterocycles and quinone with organoboron species via innate C–H functionalization: application in total synthesis …

PP Singh, SK Aithagani, M Yadav… - The Journal of …, 2013 - ACS Publications
Here, we report an iron-catalyzed cross-coupling reaction of electron-deficient heterocycles
and quinone with organoboron species via innate C–H functionalization. Iron (II) …

Synthesis of Pyrazines from Rhodium-Catalyzed Reaction of 2H-Azirines with N-Sulfonyl 1,2,3-Triazoles

T Ryu, Y Baek, PH Lee - The Journal of organic chemistry, 2015 - ACS Publications
An efficient synthetic route to a wide range of trisubstituted pyrazines is developed from Rh-
catalyzed reaction of 2 H-azirines with N-sulfonyl-1, 2, 3-triazoles through the elimination of …

Straightforward access to pyrazines, piperazinones, and quinoxalines by reactions of 1, 2-diaza-1, 3-butadienes with 1, 2-diamines under solution, solvent-free, or …

D Aparicio, OA Attanasi, P Filippone… - The Journal of …, 2006 - ACS Publications
The preparation of tetrahydropyrazines, dihydropyrazines, pyrazines, piperazinones, and
quinoxalines by 1, 4-addition of 1, 2-diamines to 1, 2-diaza-1, 3-butadienes bearing …