Successful pregnancy requires carefully-coordinated communications between the mother
and fetus. Immune cells and cytokine signaling pathways participate as mediators of these …

The immune cells that reside at the interface between the placenta and uterus are thought to
play many important roles in pregnancy. Recent work has revealed that the composition and …

Introduction The pro‐and anti‐inflammatory cytokines play crucial role in the development
and functions of placenta. Any changes in these cytokines may be associated with many …

Inflammation mediated by both innate and adaptive immune cells is necessary for several
important processes during pregnancy. Pro-inflammatory immune cell activation plays a …

Progress in our understanding of the role of the maternal immune system during healthy
pregnancy will help us better understand the role of the immune system in adverse …

Although much progress is being made in understanding the molecular pathways in the
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …

Pregnancy causes physiological and immunological adaptations that allow the mother and
fetus to communicate with precision in order to promote a healthy pregnancy. At the same …

During pregnancy, the maternal immune system is challenged by the presence of the fetus,
which must be tolerated despite being semiallogeneic. Uterine mucosal (or decidual) …

Natural killer (NK) cells accumulate at the maternal–fetal interface in large numbers, but their
exact roles in successful pregnancy remain poorly defined. Here, we provide evidence that …

Placentation is a reproductive adaptation that permits fetal growth and development within
the protected confines of the female reproductive tract. Through this important role, the …