Non-coding RNAs in disease: from mechanisms to therapeutics
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
Targeting the PDGF/PDGFR signaling pathway for cancer therapy: A review
X Zou, XY Tang, ZY Qu, ZW Sun, CF Ji, YJ Li… - International Journal of …, 2022 - Elsevier
Platelet-derived growth factors (PDGFs) and PDGF receptors (PDGFRs) are expressed in a
variety of tumors. Activation of the PDGF/PDGFR signaling pathway is associated with …
variety of tumors. Activation of the PDGF/PDGFR signaling pathway is associated with …
Noncoding RNAs and RNA-binding proteins: Emerging governors of liver physiology and metabolic diseases
C Sommerauer, C Kutter - American Journal of Physiology …, 2022 - journals.physiology.org
The liver holds central roles in detoxification, energy metabolism, and whole body
homeostasis but can develop malignant phenotypes when being chronically overwhelmed …
homeostasis but can develop malignant phenotypes when being chronically overwhelmed …
Unique role for lncRNA HOTAIR in defining depot-specific gene expression patterns in human adipose-derived stem cells
Accumulation of fat above the waist is an important risk factor in developing obesity-related
comorbidities independently of BMI or total fat mass. Deciphering the gene regulatory …
comorbidities independently of BMI or total fat mass. Deciphering the gene regulatory …
Y-box binding protein 1: Unraveling the multifaceted role in cancer development and therapeutic potential
Y-box binding protein 1 (YBX1), a member of the Cold Shock Domain protein family, is
overexpressed in various human cancers and is recognized as an oncogenic gene …
overexpressed in various human cancers and is recognized as an oncogenic gene …
LncRNA profiles of Cyanidin-3-O-glucoside ameliorated Zearalenone-induced damage in porcine granulosa cells
Long non-coding RNA (lncRNA), a class of RNA molecules with transcripts longer than 200
nt, is crucial for maintaining animal reproductive function. Zearalenone (ZEN) damaged …
nt, is crucial for maintaining animal reproductive function. Zearalenone (ZEN) damaged …
Dynamic changes in LINC00458/HBL1 lncRNA expression during hiPSC differentiation to cardiomyocytes
Long non-coding RNAs (lncRNAs) constitute the largest and most diverse class of non-
coding RNAs. They localize to the nucleus, cytoplasm, or both compartments, and regulate …
coding RNAs. They localize to the nucleus, cytoplasm, or both compartments, and regulate …
[HTML][HTML] Targeting PDGF/PDGFR Signaling Pathway by microRNA, lncRNA, and circRNA for Therapy of Vascular Diseases: A Narrow Review
CN Ma, SR Shi, XY Zhang, GS Xin, X Zou, WL Li… - Biomolecules, 2024 - mdpi.com
Despite the significant progress in diagnostic and therapeutic strategies, vascular diseases,
such as cardiovascular diseases (CVDs) and respiratory diseases, still cannot be …
such as cardiovascular diseases (CVDs) and respiratory diseases, still cannot be …
[HTML][HTML] The intraviral protein-protein interaction of SARS-CoV-2 reveals the key role of N protein in virus-like particle assembly
M Chen, C Yan, F Qin, L Zheng… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Intraviral protein-protein interactions (PPIs) of SARS-CoV-2 in host cells may provide useful
information for deep understanding of virology of SARS-CoV-2. In this study, 22 of 55 …
information for deep understanding of virology of SARS-CoV-2. In this study, 22 of 55 …
Diverse regulation of YB-1 and YB-3 abundance in mammals
IA Eliseeva, EM Sogorina, EA Smolin… - Biochemistry …, 2022 - Springer
Abstract YB proteins are DNA/RNA binding proteins, members of the family of proteins with
cold shock domain. Role of YB proteins in the life of cells, tissues, and whole organisms is …
cold shock domain. Role of YB proteins in the life of cells, tissues, and whole organisms is …