Review of the roles of conjugated linoleic acid in health and disease

B Yang, H Chen, C Stanton, RP Ross, H Zhang… - Journal of Functional …, 2015 - Elsevier
Dietary fatty acids (FA) are increasingly recognized as major biologic regulators and have
properties that relate to health outcomes and disease. Conjugated linoleic acid (CLA) is a …

Dietary polyunsaturated fatty acids as inducers of apoptosis: implications for cancer

S Serini, E Piccioni, N Merendino, G Calviello - Apoptosis, 2009 - Springer
It has recently become clear the role played by alterations in apoptosis during the
development of several chronic diseases (ie inflammatory, neurodegenerative and …

[HTML][HTML] Effect of oxidative stress on plasma membrane fluidity of THP-1 induced macrophages

C De La Haba, JR Palacio, P Martínez… - Biochimica et Biophysica …, 2013 - Elsevier
Plasma membrane is one of the preferential targets of reactive oxygen species which cause
lipid peroxidation. This process modifies membrane properties such as membrane fluidity, a …

Trans-10, cis-12 conjugated linoleic acid induced cell death in human colon cancer cells through reactive oxygen species-mediated ER stress

AS Pierre, M Minville-Walz, C Fèvre, A Hichami… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Dietary conjugated linoleic acids (CLA) are fatty acid isomers with anticancer activities
produced naturally in ruminants or from vegetable oil processing. The anticancer effects of …

[HTML][HTML] In vitro effects of conjugated linoleic acid (CLA) on inflammatory functions of bovine monocytes

G Ávila, C Catozzi, D Pravettoni, G Sala, P Martino… - Journal of dairy …, 2020 - Elsevier
The conjugated linoleic acid (CLA) isomers, a group of naturally occurring isomers of the
essential fatty acid (FA) linoleic acid, have received special attention in animal and human …

PPAR Activation Induces M1 Macrophage Polarization via cPLA2‐COX‐2 Inhibition, Activating ROS Production against Leishmania mexicana

JA Díaz-Gandarilla, C Osorio-Trujillo… - BioMed research …, 2013 - Wiley Online Library
Defence against Leishmania depends upon Th1 inflammatory response and, a major
problem in susceptible models, is the turnoff of the leishmanicidal activity of macrophages …

The impact of dietary fatty acids on macrophage cholesterol homeostasis

M da Silva Afonso, G Castilho, MSF Lavrador… - The Journal of …, 2014 - Elsevier
The impact of dietary fatty acids in atherosclerosis development may be partially attributed to
their effect on macrophage cholesterol homeostasis. This process is the result of interplay …

Modulation of the biomarkers of inflammation and oxidative stress by ruminant trans fatty acids and dairy proteins in vascular endothelial cells (HUVEC)

MS Da Silva, JF Bilodeau, J Larose, K Greffard… - … and Essential Fatty …, 2017 - Elsevier
This study aimed to determine whether dairy macronutrients alter markers of inflammation
and oxidative stress in endothelial cells. Human endothelial cells (HUVEC) were treated …

[HTML][HTML] Conjugated linoleic acid (CLA) modulates bovine peripheral blood mononuclear cells (PBMC) proteome in vitro

G Ávila, F Ceciliani, D Viala, S Dejean, G Sala… - Journal of …, 2024 - Elsevier
Conjugated linoleic acid (CLA) is a group of natural isomers of the n-6 polyunsaturated fatty
acid (PUFA) linoleic acid, exerting biological effects on cow physiology. This study assessed …

Conjugated linoleic acid-induced apoptosis in mouse mammary tumor cells is mediated by both G protein coupled receptor-dependent activation of the AMP-activated …

YC Hsu, MM Ip - Cellular signalling, 2011 - Elsevier
Conjugated linoleic acid (CLA) has shown chemopreventive activity in several
tumorigenesis models, in part through induction of apoptosis. We previously demonstrated …