Inflammatory bowel disease (IBD) comprises ulcerative colitis (UC) and Crohn's disease
(CD). IBD etiopathology is multifactorial and involves alteration of immune cells and chronic …

Glucocorticoid hormones regulate essential body functions in mammals, control cell
metabolism, growth, differentiation, and apoptosis. Importantly, they are potent suppressors …

The circadian rhythms are daily oscillations in various biological processes that are
regulated by an endogenous clock. Disruption of these rhythms has been associated with …

Glucocorticoids are anti-inflammatory drugs that are widely used for the treatment of
numerous (autoimmune) inflammatory diseases. They exert their actions by binding to the …

Inflammation is a beneficial host reaction to tissue damage and has the essential primary
purpose of restoring tissue homeostasis. Inflammation plays a major role in containing and …

Glucocorticoids (GCs) represent the mainstay of current anti‐inflammatory and
immunosuppressive strategies, mediating effects that mostly result in transcriptional …

Glucocorticoids (GCs) are steroidal ligands for the GC receptor (GR), which can function as
a ligand-activated transcription factor. These steroidal ligands and derivatives thereof are …

Corticosteroid hormones play an important role in the control of vascular smooth muscle
tone by their permissive effects in potentiating vasoactive responses to catecholamines …

The identification of key genes in transcriptomic data constitutes a huge challenge. Our
review of microarray reports revealed 88 genes whose transcription is consistently regulated …

Taking into consideration that glucocorticoid (GC) hormones have been used clinically for
over half a century and that more than 20 yr have passed since the cloning of the GC …