Ovarian cancer (OC) represents one of the most letal cancers in women. The aim of surgical
treatment consists of complete cytoreduction in advanced stages and a surgical staging in …

Simple Summary Ovarian cancer has the highest mortality rate of any type of gynecological
cancer because it is diagnosed in advanced stages and its recurrence rate is about 80 …

Background: Hyperthermic intraperitoneal chemotherapy (HIPEC) after cytoreductive
surgery has been extensively studied in patients with peritoneal carcinomatosis, and it holds …

Highlights•Surgery plays a critical role in many aspects of ovarian cancer management.•
Combined with cytoreductive surgery, HIPEC is an emerging modality for ovarian …

Introduction Ovarian cancer is the most lethal gynecologic malignancy. Although treatment
with hyperthermic intraperitoneal chemotherapy (HIPEC) has shown promising results, its …

Background The utility of heated intraperitoneal chemotherapy (HIPEC) in the management
of epithelial ovarian cancer (EOC) has been assessed in several randomised clinical trials …

The ovarian cancer recurrence occurs in 75% of patients with advanced FIGO stage, and its
treatment is a challenge for the oncologist in gynecology. The standard treatment of …

This study aims to evaluate the drug distribution, tissue concentrations, penetration depth,
pharmacokinetic properties, and toxicities after rotational intraperitoneal pressurized aerosol …

Simple Summary The vast majority of patients with epithelial ovarian carcinoma (OC) will
relapse during the natural history of their disease. The role of cytoreductive surgery (CRS) in …

Introduction: Despite, the strong rationale and evidence of the benefit of postoperative
intraperitoneal chemotherapy in advanced ovarian cancer, it has not been widely adopted …