Extracellular matrix and colorectal cancer: how surrounding microenvironment affects cancer cell behavior?

S Crotti, M Piccoli, F Rizzolio… - Journal of cellular …, 2017 - Wiley Online Library
Colorectal cancer (CRC) whit more than a million of new cases per year is one of the most
common registered cancers worldwide with few treatment options especially for advanced …

Host and tumor derived MMP13 regulate extravasation and establishment of colorectal metastases in the liver

AM Mendonsa, MN VanSaun, A Ustione, DW Piston… - Molecular cancer, 2015 - Springer
Background Non alcoholic fatty liver disease (NAFLD) is one of the most common liver
diseases in the United States and worldwide. Our studies have previously shown an …

Relation of glypican-3 and E-cadherin expressions to clinicopathological features and prognosis of mucinous and non-mucinous colorectal adenocarcinoma

AARM Foda, MA Mohammad, A Abdel-Aziz… - Tumor Biology, 2015 - Springer
Abstract Glypican-3 (GPC3) is a member of the membrane-bound heparin sulfate
proteoglycans. E-cadherin is an adhesive receptor that is believed to act as a tumor …

Association of Clinicopathological Factors With MMP13 (rs2252070) Gene Polymorphism in Swedish Patients With Colorectal Cancer

S van Nguyen, L Shamoun, K Landerholm, D Wågsäter… - in vivo, 2024 - iv.iiarjournals.org
Background/Aim: Matrix metalloproteinase 13 (MMP13) has been reported to be involved in
tumor development and progression, including of colorectal cancer (CRC). This study aimed …

Colorectal signet ring cell carcinoma: Influence of EGFR, E-cadherin and MMP-13 expression on clinicopathological features and prognosis

AARM Foda, AA Aziz, MA Mohamed - Annals of Diagnostic Pathology, 2018 - Elsevier
Signet ring cell carcinoma (SRCC) is unique rare subtype of mucin-producing colorectal
adenocarcinoma characterized by presence of signet ring cells, in> 50% of the tumor tissue …

Role of ERCC1 expression in colorectal adenoma-carcinoma sequence and relation to other mismatch repair proteins expression, clinicopathological features and …

A Palicelli, A Shebl, R Boldorini, K Elnaghi… - Indian Journal of …, 2019 - journals.lww.com
Background: There are several DNA repair pathways that protect cellular DNA from injury,
such as nucleotide excision repair (NER) and mismatch repair (MMR). The protein product …

[PDF][PDF] Rare mucinous colorectal adenocarcinoma: analysis of the epidemiological factors in relation to survival in Egyptian patients

AK El-Hawary, AA Aziz, A Hosni, KR Zalata… - American Journal of …, 2014 - academia.edu
Colorectal carcinoma (CRC) is one of the leading causes of cancer related deaths; in Egypt
it constitutes 6.5% of all cancers. Previous studies have shown conflicting results on …

Colorectal adenocarcinoma with mucinous component: relation of MMP‐13, EGFR, and E‐cadherin expressions to clinicopathological features and prognosis

AARM Foda, AK El‐Hawary, AA Aziz - Apmis, 2015 - Wiley Online Library
The aim of this study was to compare colorectal adenocarcinoma with mucinous component,
ordinary adenocarcinoma (OA) and mucinous adenocarcinoma (MA) regarding …

Aberrant Expression of Calretinin, D2–40 and Mesothelin in Mucinous and Non-Mucinous Colorectal Carcinomas and Relation to Clinicopathological Features and …

AARM Foda, AK El-Hawary, H Hamed - Pathology & Oncology Research, 2016 - Springer
CRC is a heterogeneous disease in terms of morphology, invasive behavior, metastatic
capacity, and clinical outcome. Recently, many so-called mesothelial markers, including …

Aberrant expressions of c-KIT and DOG-1 in mucinous and nonmucinous colorectal carcinomas and relation to clinicopathologic features and prognosis

AARM Foda, MA Mohamed - Annals of diagnostic pathology, 2015 - Elsevier
Abstract c-KIT and DOG-1 are 2 highly expressed proteins in gastrointestinal stromal tumors.
Few studies had investigated c-KIT, but not DOG-1, expression in colorectal carcinoma …