Malaria is among one of the most devastating and deadliest parasitic disease in the world
claiming millions of lives every year around the globe. It is a mosquito-borne infectious …

ABSTRACT Introduction The 1, 2, 3-triazole ring occupies an important space in medicinal
chemistry due to its unique structural properties, synthetic versatility and pharmacological …

Cancer is one of the major causes of mortality and morbidity worldwide. Substantial
research efforts have been made to develop new chemical entities with improved anticancer …

Abstract: 1, 2, 3-triazole skeleton is a privileged building block for the discovery of new
promising anticancer agents. In this report, new 1, 4-disubstituted 1, 2, 3-triazoles with the …

The persistence of drug resistance poses a significant obstacle to the advancement of
efficacious malaria treatments. The remarkable efficacy displayed by 1, 2, 3-triazole-based …

A simple and novel metal-free reduction of azides to amines in the presence of DBU is
reported. Aromatic and sulfonyl azides are typically used to give the desired amines in …

Malaria is a very destructive and lethal parasitic disease that causes significant mortality
worldwide, resulting in the loss of millions of lives annually. The uncontrolled intake of …

Herein we describe synthesis and evaluation of 4-aminoquinoline derivatives as anticancer
agents. By using Friedlander type condensation and cyclization reactions, the new …

The clinical resistance towards malarial parasites has rendered many antimalarials
ineffective, likely due to a lack of understanding of time of action and stage specificity of all …

Malaria remains a severe infectious disease caused by Plasmodium parasites among the
primarily afflicting impoverished populations. According to World Health Organization (WHO) …