Background Existing meta-analyses on omega-3 polyunsaturated fatty acids and their anti-
inflammatory effects have reported uncertain findings. The current umbrella meta-analysis …

The transcription factor NRF2 and its endogenous inhibitor KEAP1 play a crucial role in the
maintenance of cellular redox homeostasis by regulating the gene expression of diverse …

Unsaturated fatty acids might be involved in the prevention of and improvement in mental
disorders, but the evidence on these associations has not been comprehensively assessed …

Question This umbrella review and guidelines aimed to provide evidence to support the
rational choice of selected adjunctive therapies for schizophrenia. Study selection and …

Comprehending the pathogenesis of schizophrenia represents a challenge for global
mental health. To date, although it is evident that alterations in dopaminergic, serotonergic …

Metabolic disturbances and obesity are major cardiovascular risk factors in patients with
schizophrenia, resulting in a higher mortality rate and shorter life expectancy compared with …

Due to their vital physiological functions, nutritional fatty acids have great potential as
nutraceutical food supplements for preventing an array of diseases such as inflammation …

Schizophrenia, a serious psychiatric disorder, is among the top 10 global causes of disability
and affects nearly 1% of the world population. Antipsychotics constitute the best treatment for …

Despite decades of research on the pathophysiology of depression, the development of new
therapeutic interventions has been slow, and no biomarkers of treatment response have …

A complete blood count (CBC) is a routinely performed blood examination. Only a few
studies assess the relationship between CBC and oxidative stress (OS) in schizophrenia …