Antimalarial drug discovery: Progress and approaches

JL Siqueira-Neto, KJ Wicht, K Chibale… - Nature Reviews Drug …, 2023 - nature.com
Recent antimalarial drug discovery has been a race to produce new medicines that
overcome emerging drug resistance, whilst considering safety and improving dosing …

[HTML][HTML] Antiparasitics in animal health: quo vadis?

PM Selzer, C Epe - Trends in parasitology, 2021 - cell.com
Antiparasitics acting on endo-or ectoparasites represent the second largest segment of the
global animal health market, accounting for 23% of market share. However, relatively few …

[HTML][HTML] The need for new vector control approaches targeting outdoor biting Anopheline malaria vector communities

S Sougoufara, EC Ottih, F Tripet - Parasites & Vectors, 2020 - Springer
Since the implementation of Roll Back Malaria, the widespread use of insecticide-treated
nets (ITNs) and indoor residual spraying (IRS) is thought to have played a major part in the …

[HTML][HTML] A roadmap for the development of ivermectin as a complementary malaria vector control tool

TI Roadmappers - The American journal of tropical medicine and …, 2020 - ncbi.nlm.nih.gov
In the context of stalling progress against malaria, resistance of mosquitoes to insecticides,
and residual transmission, mass drug administration (MDA) of ivermectin, an endectocide …

[HTML][HTML] Insecticide-treated livestock: a potential One Health approach to malaria control in Africa

P Ruiz-Castillo, C Rist, R Rabinovich, C Chaccour - Trends in parasitology, 2022 - cell.com
New vector-control tools are urgently needed to reduce malaria in areas where there is
significant transmission after deployment of indoor residual spraying (IRS) and insecticide …

Ivermectin as a novel complementary malaria control tool to reduce incidence and prevalence: a modelling study

HC Slater, BD Foy, K Kobylinski… - The Lancet Infectious …, 2020 - thelancet.com
Background Ivermectin is a potential new vector control tool to reduce malaria transmission.
Mosquitoes feeding on a bloodmeal containing ivermectin have a reduced lifespan …

Discovery, development, chemical diversity and design of isoxazoline-based insecticides

IL Gonçalves, GM das Neves, LP Kagami… - Bioorganic & Medicinal …, 2021 - Elsevier
Isoxazoline is a 5-membered heterocycle present in the active compounds of many
commercial veterinary anti-ectoparasitic products. The molecular target of isoxazolines is the …

[HTML][HTML] A testing cascade to identify repurposed insecticides for next-generation vector control tools: screening a panel of chemistries with novel modes of action …

R Lees, G Praulins, R Davies, F Brown… - Gates open …, 2019 - ncbi.nlm.nih.gov
Background: With insecticide resistance in malaria vectors spreading in geographical range
and intensity, there is a need for compounds with novel modes of action to maintain the …

[HTML][HTML] Leishmania infection in cats and feline leishmaniosis: An updated review with a proposal of a diagnosis algorithm and prevention guidelines

A Pereira, C Maia - Current research in parasitology & vector-borne …, 2021 - Elsevier
Leishmaniosis is a vector-borne disease caused by protozoans of the genus Leishmania,
which are transmitted to vertebrates, including cats, through the bites of female …

Toxicity and sublethal effects of fluralaner on Spodoptera litura Fabricius (Lepidoptera: Noctuidae)

D Liu, ZQ Jia, YC Peng, CW Sheng, T Tang… - Pesticide biochemistry …, 2018 - Elsevier
The increasing occurrence of resistance to chemical insecticides in insect pest populations
is a serious threat to the integrity of current pest management strategies, and exploring new …