Antimalarial drug discovery: Progress and approaches
Recent antimalarial drug discovery has been a race to produce new medicines that
overcome emerging drug resistance, whilst considering safety and improving dosing …
overcome emerging drug resistance, whilst considering safety and improving dosing …
[HTML][HTML] Antiparasitics in animal health: quo vadis?
PM Selzer, C Epe - Trends in parasitology, 2021 - cell.com
Antiparasitics acting on endo-or ectoparasites represent the second largest segment of the
global animal health market, accounting for 23% of market share. However, relatively few …
global animal health market, accounting for 23% of market share. However, relatively few …
[HTML][HTML] The need for new vector control approaches targeting outdoor biting Anopheline malaria vector communities
S Sougoufara, EC Ottih, F Tripet - Parasites & Vectors, 2020 - Springer
Since the implementation of Roll Back Malaria, the widespread use of insecticide-treated
nets (ITNs) and indoor residual spraying (IRS) is thought to have played a major part in the …
nets (ITNs) and indoor residual spraying (IRS) is thought to have played a major part in the …
[HTML][HTML] A roadmap for the development of ivermectin as a complementary malaria vector control tool
TI Roadmappers - The American journal of tropical medicine and …, 2020 - ncbi.nlm.nih.gov
In the context of stalling progress against malaria, resistance of mosquitoes to insecticides,
and residual transmission, mass drug administration (MDA) of ivermectin, an endectocide …
and residual transmission, mass drug administration (MDA) of ivermectin, an endectocide …
[HTML][HTML] Insecticide-treated livestock: a potential One Health approach to malaria control in Africa
P Ruiz-Castillo, C Rist, R Rabinovich, C Chaccour - Trends in parasitology, 2022 - cell.com
New vector-control tools are urgently needed to reduce malaria in areas where there is
significant transmission after deployment of indoor residual spraying (IRS) and insecticide …
significant transmission after deployment of indoor residual spraying (IRS) and insecticide …
Ivermectin as a novel complementary malaria control tool to reduce incidence and prevalence: a modelling study
Background Ivermectin is a potential new vector control tool to reduce malaria transmission.
Mosquitoes feeding on a bloodmeal containing ivermectin have a reduced lifespan …
Mosquitoes feeding on a bloodmeal containing ivermectin have a reduced lifespan …
Discovery, development, chemical diversity and design of isoxazoline-based insecticides
IL Gonçalves, GM das Neves, LP Kagami… - Bioorganic & Medicinal …, 2021 - Elsevier
Isoxazoline is a 5-membered heterocycle present in the active compounds of many
commercial veterinary anti-ectoparasitic products. The molecular target of isoxazolines is the …
commercial veterinary anti-ectoparasitic products. The molecular target of isoxazolines is the …
[HTML][HTML] A testing cascade to identify repurposed insecticides for next-generation vector control tools: screening a panel of chemistries with novel modes of action …
R Lees, G Praulins, R Davies, F Brown… - Gates open …, 2019 - ncbi.nlm.nih.gov
Background: With insecticide resistance in malaria vectors spreading in geographical range
and intensity, there is a need for compounds with novel modes of action to maintain the …
and intensity, there is a need for compounds with novel modes of action to maintain the …
[HTML][HTML] Leishmania infection in cats and feline leishmaniosis: An updated review with a proposal of a diagnosis algorithm and prevention guidelines
A Pereira, C Maia - Current research in parasitology & vector-borne …, 2021 - Elsevier
Leishmaniosis is a vector-borne disease caused by protozoans of the genus Leishmania,
which are transmitted to vertebrates, including cats, through the bites of female …
which are transmitted to vertebrates, including cats, through the bites of female …
Toxicity and sublethal effects of fluralaner on Spodoptera litura Fabricius (Lepidoptera: Noctuidae)
The increasing occurrence of resistance to chemical insecticides in insect pest populations
is a serious threat to the integrity of current pest management strategies, and exploring new …
is a serious threat to the integrity of current pest management strategies, and exploring new …