Objectives Systemic administration of lipopolysaccharide induces neuroinflammation
leading to cognitive deficit and memory impairment. Herein, we investigated the effects of p …

Oxidative stress plays a pivotal part in the manifestation of neuroinflammation, which further
leads to neurodegenerative diseases like Alzheimer's disease (AD). Systemic administration …

Constraint-induced movement therapy after cerebral ischemia stimulates axonal growth by
decreasing expression levels of Nogo-A, RhoA, and Rho-associated kinase (ROCK) in the …

Adjudge the neuroprotective ability of Ellagic acid (EA) as a constructive herbal drug to
impede cholinergic dysfunctions and oxidative stress in Alzheimer's disease (AD) in …

The Morris water maze test (MWM) is one of the most popular and established behavioral
tests to evaluate rodents' spatial learning ability. The conventional training period is around …

Extracellular deposition of Beta-amyloid peptide (Aβ) is the main finding in the
pathophysiology of Alzheimer's disease (AD), which damages cholinergic neurons through …

The theta rhythm is necessary for hippocampal-dependent spatial learning. It has been
proposed that each hippocampal stratum can generate a current theta dipole. Therefore …

Objective To investigate the differential effects of left versus right cerebral hemisphere on the
infarct volume and behavioral function following focal cerebral ischemia in rats. Methods …

Although there are number of studies showing that phosphodiesterase (PDE) 4 and 5
inhibitors affect different kinds of memory, their effects on spatial memory consolidation in …

Cognitive impairment responses are important research topics in the study of degenerative
brain diseases as well as in understanding of human mental activities. To compare …