Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …

Cyclopeptides are considered as one of the most important classes of compounds derived
from marine sources, due to their structural diversity and a myriad of their biological and …

The determination of the enantiomeric excess and absolute configuration of chiral
compounds is indispensable in synthetic, pharmaceutical, and biological chemistry. In this …

Chirality recognition of pharmaceutical products plays a significant part in asymmetric
synthesis, stereoselective catalysis, supramolecular chemistry, and the development of new …

Secondary metabolites from land and marine (micro) organisms have been at the focus of
the drug discovery process for many years. One of the reasons for this success is nature's …

Direct entry to optically pure 2-amino-2′-hydroxy-1, 1′-binaphthyl (NOBIN) derivatives by
an iron-catalyzed stereoselective oxidative cross-coupling reaction between 2-naphthol and …

New arylamide-and arylthiourea-based chiral solvating agents (CSAs) were synthesized
starting from commercially available isomannide and isosorbide. The two natural isohexides …

A series of small-membered heterocycle probes, so-called azaheterocycle-containing
diphenylmethanol chiral solvating agents (CSAs), have been developed for NMR …

A chiral aluminum solvating agent (CASA) was demonstrated to be a general and efficient
reagent for 1H NMR chiral analysis of alcohols. The sodium salt of the CASA (CASA-Na) …

A simple strategy for configurational assignments of alpha-amino acids has been developed
by comparison of the proton NMR chemical shift values of the alpha hydrogens of N …