Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the devastating global COVID-19 pandemic announced by WHO in March 2020. Through …

Over three years' pandemic of 2019 novel coronavirus disease (COVID-19), multiple
variants and novel subvariants have emerged successively, outcompeted earlier variants …

The emergence of SARS-CoV-2 variants alters the efficacy of existing immunity, whether
arisen naturally or through vaccination. Understanding the structure of the viral spike assists …

The structure and post-translational processing of the SARS-CoV-2 spike glycoprotein (S) is
intimately associated with the function of the virus and of sterilising vaccines. The surface of …

Functional and epidemiological data suggest that N-linked glycans on the SARS-CoV-2
Spike protein may contribute to viral infectivity. To investigate this, we created a panel of N-to …

Coronavirus porcine epidemic diarrhea virus (PEDV) is classified in the genus
Alphacoronavirus, family Coronaviridae that encodes the only accessory protein, ORF3 …

The combined inhibition of endoplasmic reticulum (ER) α-glucosidases I and II has been
shown to inhibit replication of a broad range of viruses that rely on ER protein quality control …

The SARS-CoV-2 virus rapidly spread worldwide, threatening public health. Since it
emerged, the scientific community has been engaged in the development of effective …

Characterization of protein glycosylation by tandem mass spectrometry remains challenging
owing to the vast diversity of oligosaccharides bound to proteins, the variation in …

The spike protein receptor-binding domain (RBD) of SARS-CoV-2 binds directly to
angiotensin-converting enzyme 2 (ACE2), mediating the host cell entry of SARS-CoV-2 …