Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and …
JC Frisvad, LLH Møller, TO Larsen, R Kumar… - Applied Microbiology …, 2018 - Springer
This review presents an update on the current knowledge of the secondary metabolite
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …
Oxidative cyclization in natural product biosynthesis
MC Tang, Y Zou, K Watanabe, CT Walsh… - Chemical …, 2017 - ACS Publications
Oxidative cyclizations are important transformations that occur widely during natural product
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …
Taxonomy of Aspergillus section Flavi and their production of aflatoxins, ochratoxins and other mycotoxins
JC Frisvad, V Hubka, CN Ezekiel, SB Hong… - Studies in …, 2019 - ingentaconnect.com
Aflatoxins and ochratoxins are among the most important mycotoxins of all and producers of
both types of mycotoxins are present in Aspergillus section Flavi, albeit never in the same …
both types of mycotoxins are present in Aspergillus section Flavi, albeit never in the same …
Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action
Bioactive natural products have evolved to inhibit specific cellular targets and have served
as lead molecules for health and agricultural applications for the past century,–. The post …
as lead molecules for health and agricultural applications for the past century,–. The post …
Deciphering chemical logic of fungal natural product biosynthesis through heterologous expression and genome mining
Covering: 2010 to 2022 Heterologous expression of natural product biosynthetic gene
clusters (BGCs) has become a widely used tool for genome mining of cryptic pathways …
clusters (BGCs) has become a widely used tool for genome mining of cryptic pathways …
Class II terpene cyclases: structures, mechanisms, and engineering
Covering: up to July 2023 Terpene cyclases (TCs) catalyze some of the most complicated
reactions in nature and are responsible for creating the skeletons of more than 95 000 …
reactions in nature and are responsible for creating the skeletons of more than 95 000 …
[HTML][HTML] Developing fungal heterologous expression platforms to explore and improve the production of natural products from fungal biodiversity
X Meng, Y Fang, M Ding, Y Zhang, K Jia, Z Li… - Biotechnology …, 2022 - Elsevier
Natural products from fungi represent an important source of biologically active metabolites
notably for therapeutic agent development. Genome sequencing revealed that the number …
notably for therapeutic agent development. Genome sequencing revealed that the number …
Terpene synthases in disguise: enzymology, structure, and opportunities of non-canonical terpene synthases
Covering: up to July 2019 Terpene synthases (TSs) are responsible for generating much of
the structural diversity found in the superfamily of terpenoid natural products. These elegant …
the structural diversity found in the superfamily of terpenoid natural products. These elegant …
Detecting and prioritizing biosynthetic gene clusters for bioactive compounds in bacteria and fungi
Secondary metabolites (SM) produced by fungi and bacteria have long been of exceptional
interest owing to their unique biomedical ramifications. The traditional discovery of new …
interest owing to their unique biomedical ramifications. The traditional discovery of new …
Strategies for engineering natural product biosynthesis in fungi
E Skellam - Trends in Biotechnology, 2019 - cell.com
Fungi are a prolific source of bioactive compounds, some of which have been developed as
essential medicines and life-enhancing drugs. Genome sequencing has revealed that fungi …
essential medicines and life-enhancing drugs. Genome sequencing has revealed that fungi …