The many actions of insulin in skeletal muscle, the paramount tissue determining glycemia
As the principal tissue for insulin-stimulated glucose disposal, skeletal muscle is a primary
driver of whole-body glycemic control. Skeletal muscle also uniquely responds to muscle …
driver of whole-body glycemic control. Skeletal muscle also uniquely responds to muscle …
GLUT4 On the move
DJ Fazakerley, F Koumanov, GD Holman - Biochemical Journal, 2022 - portlandpress.com
Insulin rapidly stimulates GLUT4 translocation and glucose transport in fat and muscle cells.
Signals from the occupied insulin receptor are translated into downstream signalling …
Signals from the occupied insulin receptor are translated into downstream signalling …
Exocytosis proteins: typical and atypical mechanisms of action in skeletal muscle
J Hwang, DC Thurmond - Frontiers in Endocrinology, 2022 - frontiersin.org
Insulin-stimulated glucose uptake in skeletal muscle is of fundamental importance to prevent
postprandial hyperglycemia, and long-term deficits in insulin-stimulated glucose uptake …
postprandial hyperglycemia, and long-term deficits in insulin-stimulated glucose uptake …
Measurement of GLUT4 traffic to and from the cell surface in muscle cells
Elevated blood glucose following a meal is cleared by insulin‐stimulated glucose entry into
muscle and fat cells. The hormone increases the amount of the glucose transporter GLUT4 …
muscle and fat cells. The hormone increases the amount of the glucose transporter GLUT4 …
[PDF][PDF] Flow cytometry protocol for GLUT4-myc detection on cell surfaces
E Zanni-Ruiz, LS Mayorga, MA Pavarotti - Bioscience Reports, 2024 - portlandpress.com
Insulin and muscle contraction trigger GLUT4 translocation to the plasma membrane, which
increases glucose uptake by muscle cells. Insulin resistance and Type 2 diabetes are the …
increases glucose uptake by muscle cells. Insulin resistance and Type 2 diabetes are the …
Plasma proteomic signatures of adiposity are associated with cardiovascular risk factors and type 2 diabetes risk in a multi-ethnic Asian population
The molecular mechanisms connecting obesity and cardiometabolic diseases are not fully
understood. We evaluated the associations between body mass index (BMI), waist …
understood. We evaluated the associations between body mass index (BMI), waist …
Transcriptomic profiling on localized gastric cancer identified CPLX1 as a gene promoting malignant phenotype of gastric cancer and a predictor of recurrence after …
H Tanaka, M Kanda, D Shimizu, C Tanaka… - Journal of …, 2022 - Springer
Background Localized gastric cancer (GC) becomes fatal once recurring. We still have room
for improving their prognoses. Methods Transcriptomic analysis was done on surgically …
for improving their prognoses. Methods Transcriptomic analysis was done on surgically …
A new degree of complexi (n) ty in the regulation of GLUT4 trafficking
L Bertrand, M De Loof, C Beauloye… - Biochemical …, 2021 - portlandpress.com
Loss of the insulin-stimulated glucose uptake in muscle is a crucial event participating in the
defect of whole-body metabolism in type 2 diabetes. Therefore, identification by Pavarotti et …
defect of whole-body metabolism in type 2 diabetes. Therefore, identification by Pavarotti et …
Cascada de señalización de la insulina y la actividad física para el transporte de GLUT-4 y la captación de glucosa en el músculo esquelético
MA Pavarotti, M Rodríguez - Revista de la Sociedad Argentina de …, 2023 - revistasad.com
El músculo esquelético (ME), debido a su significativo tamaño y función, representa el tejido
que más energía demanda durante la actividad física. En respuesta a esta demanda, ha …
que más energía demanda durante la actividad física. En respuesta a esta demanda, ha …