Smoking is a major risk factor for a variety of diseases, including cancer and immune-
mediated inflammatory diseases. Tobacco smoke contains a mixture of chemicals, including …

Transcriptionally active chromatin is marked by tri-methylation of histone H3 at lysine 4
(H3K4me3) located after first exons and around transcription start sites. This epigenetic mark …

Abstract Methyltransferase-like 3 (METTL3) functions as an RNA methyltransferase that
controls the modification of N (6)-methyladenosine (m6A) to influence the biosynthesis …

Glioblastoma multiforme (GBM) is the most common form of brain cancer and one of the
most aggressive cancers found in humans. Most of the signs and symptoms of GBM can be …

Zebrafish (Danio rerio) is a valuable non-mammalian vertebrate model widely used to study
development and disease, including more recently cancer. The evolutionary conservation of …

Long noncoding RNAs (lncRNAs) play a critical role in the regulation of many important
cellular processes. However, the mechanisms by which lncRNAs regulate viral infection and …

Early detection improves hepatocellular carcinoma (HCC) outcomes, but better noninvasive
surveillance tools are needed. We aimed to identify and validate methylated DNA markers …

Drug resistance is a major hurdle in cancer treatment and a key cause of poor prognosis.
Epitranscriptomics and epiproteomics are crucial in cell proliferation, migration, invasion …

Secondary metabolites are divided into three classes: phenolic, terpenoid, and nitrogenous
compounds. Phenolic compounds are also known as polyphenols and include tannins …

Gastrointestinal cancer is the most common human malignancy characterized by high
lethality and poor prognosis. Emerging evidences indicate that N6-methyladenosine (m6A) …