Chemical methods for mapping cysteine oxidation
Cysteine residues in proteins are subject to diverse redox chemistry. Oxidation of cysteine to
S-nitrosocysteine, cysteine sulfenic and sulfinic acids, disulfides and persulfides are a few …
S-nitrosocysteine, cysteine sulfenic and sulfinic acids, disulfides and persulfides are a few …
The expanding landscape of the thiol redox proteome
J Yang, KS Carroll, DC Liebler - Molecular & Cellular Proteomics, 2016 - ASBMB
Cysteine occupies a unique place in protein chemistry. The nucleophilic thiol group allows
cysteine to undergo a broad range of redox modifications beyond classical thiol-disulfide …
cysteine to undergo a broad range of redox modifications beyond classical thiol-disulfide …
An evolving understanding of the S-glutathionylation cycle in pathways of redox regulation
By nature of the reversibility of the addition of glutathione to low pKa cysteine residues, the
post-translational modification of S-glutathionylation sanctions a cycle that can create a …
post-translational modification of S-glutathionylation sanctions a cycle that can create a …
From structure to redox: The diverse functional roles of disulfides and implications in disease
TJ Bechtel, E Weerapana - Proteomics, 2017 - Wiley Online Library
This review provides a comprehensive overview of the functional roles of disulfide bonds
and their relevance to human disease. The critical roles of disulfide bonds in protein …
and their relevance to human disease. The critical roles of disulfide bonds in protein …
Assessment of glutathione/glutathione disulphide ratio and S-glutathionylated proteins in human blood, solid tissues, and cultured cells
D Giustarini, G Colombo, ML Garavaglia… - Free Radical Biology …, 2017 - Elsevier
Glutathione (GSH) is the major non-protein thiol in humans and other mammals, which is
present in millimolar concentrations within cells, but at much lower concentrations in the …
present in millimolar concentrations within cells, but at much lower concentrations in the …
Redox homeostasis in photosynthetic organisms: novel and established thiol-based molecular mechanisms
Significance: Redox homeostasis consists of an intricate network of reactions in which
reactive molecular species, redox modifications, and redox proteins act in concert to allow …
reactive molecular species, redox modifications, and redox proteins act in concert to allow …
[HTML][HTML] Chicken slaughterhouse by-products: A source of protein hydrolysates to manage non-communicable diseases
N Ibarz-Blanch, JM Alcaide-Hidalgo… - Trends in Food Science …, 2023 - Elsevier
Background The poultry industry is a growing livestock sector, which generates large
volumes of by-products with negative environmental impacts that must be revalorized …
volumes of by-products with negative environmental impacts that must be revalorized …
Emerging chemistry and biology in protein glutathionylation
DSK Kukulage, NNJM Don, YH Ahn - Current opinion in chemical biology, 2022 - Elsevier
Protein S-glutathionylation serves a regulatory role in proteins and modulates distinct
biological processes implicated in health and diseases. Despite challenges in analyzing the …
biological processes implicated in health and diseases. Despite challenges in analyzing the …
Enrichment and separation techniques for large-scale proteomics analysis of the protein post-translational modifications
Comprehensive analysis of the post-translational modifications (PTMs) on proteins at
proteome level is crucial to elucidate the regulatory mechanisms of various biological …
proteome level is crucial to elucidate the regulatory mechanisms of various biological …
The application of sulfur-containing peptides in drug discovery
J Zhao, X Jiang - Chinese Chemical Letters, 2018 - Elsevier
In recent decades, peptides as potential drugs were more and more explored with the
development of non-oral medicine. There into, sulfur-containing peptide is one of the most …
development of non-oral medicine. There into, sulfur-containing peptide is one of the most …