[HTML][HTML] Is the brain a key player in glucose regulation and development of type 2 diabetes?
MH Lundqvist, K Almby, N Abrahamsson… - Frontiers in …, 2019 - frontiersin.org
Ever since Claude Bernards discovery in the mid 19th-century that a lesion in the floor of the
third ventricle in dogs led to altered systemic glucose levels, a role of the CNS in whole-body …
third ventricle in dogs led to altered systemic glucose levels, a role of the CNS in whole-body …
The unappreciated roles of the cholecystokinin receptor CCK (1) in brain functioning
S Ballaz - Reviews in the Neurosciences, 2017 - degruyter.com
The CCK (1) receptor is a G-protein-coupled receptor activated by the sulfated forms of
cholecystokinin (CCK), a gastrin-like peptide released in the gastrointestinal tract and …
cholecystokinin (CCK), a gastrin-like peptide released in the gastrointestinal tract and …
Cholecystokinin switches the plasticity of GABA synapses in the dorsomedial hypothalamus via astrocytic ATP release
KM Crosby, C Murphy-Royal, SA Wilson… - Journal of …, 2018 - Soc Neuroscience
Whether synapses in appetite-regulatory brain regions undergo long-term changes in
strength in response to satiety peptides is poorly understood. Here we show that following …
strength in response to satiety peptides is poorly understood. Here we show that following …
The effect of yellow pea protein and fibre on short-term food intake, subjective appetite and glycaemic response in healthy young men
CE Smith, RC Mollard, BL Luhovyy… - British Journal of …, 2012 - cambridge.org
Pulses are low-glycaemic foods rich in protein (20–25%), resistant starch and fibre that
suppress appetite and glycaemia. The objective of the present study was to elucidate the …
suppress appetite and glycaemia. The objective of the present study was to elucidate the …
Ghrelin infused into the dorsomedial hypothalamus of male mice increases food intake and adiposity.
Ghrelin is a 28 amino acid peptide hormone that targets the brain to promote feeding and
adiposity. The ghrelin receptor, the GHSR1a, is expressed within most hypothalamic nuclei …
adiposity. The ghrelin receptor, the GHSR1a, is expressed within most hypothalamic nuclei …
Heating and eating: Brown adipose tissue thermogenesis precedes food ingestion as part of the ultradian basic rest–activity cycle in rats
W Blessing, M Mohammed, Y Ootsuka - Physiology & behavior, 2012 - Elsevier
Laboratory rats, throughout the 24hour day, alternate between behaviorally active and non
active episodes that Kleitman called the basic rest–activity cycle (BRAC). We previously …
active episodes that Kleitman called the basic rest–activity cycle (BRAC). We previously …
[HTML][HTML] The deletion of glucagon-like peptide-1 receptors expressing neurons in the dorsomedial hypothalamic nucleus disrupts the diurnal feeding pattern and …
Y Maejima, S Yokota, M Shimizu, S Horita… - Nutrition & …, 2021 - Springer
Background Feeding rhythm disruption contributes to the development of obesity. The
receptors of glucagon-like peptide-1 (GLP-1) are distributed in the wide regions of the brain …
receptors of glucagon-like peptide-1 (GLP-1) are distributed in the wide regions of the brain …
Physiology, pathophysiology and therapeutic implications of enteroendocrine control of food intake
JA Elliott, JV Reynolds, CW le Roux… - Expert Review of …, 2016 - Taylor & Francis
Introduction: With the increasing prevalence of obesity and its associated comorbidities,
strides to improve treatment strategies have enhanced our understanding of the function of …
strides to improve treatment strategies have enhanced our understanding of the function of …
Remote control of glucose-sensing neurons to analyze glucose metabolism
A Alvarsson, SA Stanley - American Journal of Physiology …, 2018 - journals.physiology.org
The central nervous system relies on a continual supply of glucose, and must be able to
detect glucose levels and regulate peripheral organ functions to ensure that its energy …
detect glucose levels and regulate peripheral organ functions to ensure that its energy …
[HTML][HTML] Controlling feeding behavior by chemical or gene-directed targeting in the brain: what's so spatial about our methods?
AM Khan - Frontiers in Neuroscience, 2013 - frontiersin.org
Intracranial chemical injection (ICI) methods have been used to identify the locations in the
brain where feeding behavior can be controlled acutely. Scientists conducting ICI studies …
brain where feeding behavior can be controlled acutely. Scientists conducting ICI studies …