After ischemic stroke, minocycline promotes a protective response in neurons via the RNA-binding protein HuR, with a positive impact on motor performance

K Pawletko, H Jędrzejowska-Szypułka… - International Journal of …, 2023 - mdpi.com
Ischemic stroke is the most common cause of adult disability and one of the leading causes
of death worldwide, with a serious socio-economic impact. In the present work, we used a …

[HTML][HTML] Advancing Post-Stroke Depression Research: Insights from Murine Models and Behavioral Analyses

MI Mușat, B Cătălin, M Hadjiargyrou, A Popa-Wagner… - Life, 2024 - mdpi.com
Post-stroke depression (PSD) represents a significant neuropsychiatric complication that
affects between 39% and 52% of stroke survivors, leading to impaired recovery, decreased …

A meta-analysis of animal studies evaluating the effect of hydrogen sulfide on ischemic stroke: is the preclinical evidence sufficient to move forward?

S Emre Aydıngöz, A Teimoori, HG Orhan… - Naunyn-Schmiedeberg's …, 2024 - Springer
Hydrogen sulfide (H2S) is a gasotransmitter that has been studied for its potential
therapeutic effects, including its role in the pathophysiology and treatment of stroke. This …

[HTML][HTML] Chronic Administration of Ion Channel Blockers Impact Microglia Morphology and Function in a Murine Model of Alzheimer's Disease

IKS Boboc, A Cojocaru, G Nedelea, B Catalin… - International Journal of …, 2023 - mdpi.com
As the population ages, a high prevalence of multimorbidity will affect the way physicians
need to think about drug interactions. With microglia's important involvement in the …

[HTML][HTML] Genistein-3′-sodium sulfonate promotes brain functional rehabilitation in ischemic stroke rats by regulating astrocytes polarization through NF-κB signaling …

R Liu, Y Yu, Q Ge, R Feng, G Zhong, L Luo… - Chemico-Biological …, 2024 - Elsevier
The activation and polarization of astrocytes are involved in neuroinflammation and brain
functional rehabilitation after ischemic stroke. Our previous studies display the …

[PDF][PDF] Gendosz de Carrillo D, Barski JJ. After ischemic stroke, minocycline promotes a protective response in neurons via the RNA-binding protein HuR, with a positive …

K Pawletko, H Jędrzejowska-Szypułka, K Bogus… - Int J Mol Sci, 2023 - academia.edu
Ischemic stroke is the most common cause of adult disability and one of the leading causes
of death worldwide, with a serious socio-economic impact. In the present work, we used a …

Beam narrowing test: a motor index of post-stroke motor evaluation in an aged rat model of cerebral ischemia

LR Pinosanu, IKS Boboc, TA Balseanu… - Journal of Neural …, 2024 - Springer
Each year, 15 million people worldwide suffer from strokes. Consequently, researchers face
increasing pressure to develop reliable behavioural tests for assessing functional recovery …

[HTML][HTML] Investigating the Neuroprotective and Neuroregenerative Effect of Trazodone Regarding Behavioral Recovery in a BL6C57 Mice Stroke Model

IKS Boboc, AC Chirea, V Gheorman… - Current Health …, 2023 - ncbi.nlm.nih.gov
Stroke is a major cause of death and disability worldwide. Between 1990 and 2010, its
global burden increased notably with reference to the absolute number of incident events …