Since the publication of the 2018 European Society of Cardiology/European Society of
Hypertension (ESC/ESH) Guidelines for the Management of Arterial Hypertension, several …

Despite their ubiquitous presence, placebos and placebo effects retain an ambiguous and
unsettling presence in biomedicine. Specifically focused on chronic pain, this review …

The past few decades have witnessed a huge leap forward in our understanding of the
mechanistic underpinnings of pain, in normal states where it helps protect from injury, and …

Pharmacological strategies for pain management have primarily focused on dampening
ascending neurotransmission and on opioid receptor–mediated therapies. Little is known …

Background Acupuncture is often used for migraine prevention but its effectiveness is still
controversial. We present an update of our Cochrane review from 2009. Objectives To …

Background Physical therapy influences chronic pain by means of the specific ingredient of
an intervention as well as contextual factors including the setting and therapeutic alliance …

Objective Summarize the comparative effectiveness of oral non-steroidal anti-inflammatory
drugs (NSAIDs) and opioids in reducing knee osteoarthritis (OA) pain. Methods Two …

Background Acupuncture is often used for prevention of tension‐type headache but its
effectiveness is still controversial. This is an update of our Cochrane review originally …

Chronic pancreatitis is a syndrome involving inflammation, fibrosis, and loss of acinar and
islet cells which can manifest in unrelenting abdominal pain, malnutrition, and exocrine and …

A strong placebo response in psychiatric disorders has been noted for the past 50 years and
various attempts have been made to identify predictors of it, by use of meta-analyses of …