Recent advances in bioactive pyrazoles
ŞG Küçükgüzel, S Şenkardeş - European Journal of Medicinal Chemistry, 2015 - Elsevier
Pyrazole is a five membered and two-nitrogen containing heterocyclic ring. These structures
have been investigated in the development of novel compounds with hypoglycemic …
have been investigated in the development of novel compounds with hypoglycemic …
4-Thiazolidinones: the advances continue…
AC Tripathi, SJ Gupta, GN Fatima, PK Sonar… - European Journal of …, 2014 - Elsevier
The diversity in the biological response of 4-thiazolidinones has attracted the attention of
many researchers to explore this framework for its potential. It is, therefore, of prime …
many researchers to explore this framework for its potential. It is, therefore, of prime …
Recent advancement in drug design and discovery of pyrazole biomolecules as cancer and inflammation therapeutics
Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …
Synthesis of some new pyrazole-based 1, 3-thiazoles and 1, 3, 4-thiadiazoles as anticancer agents
Abstract N-(4-(Pyrazol-4-yl) thiazol-2-yl)-N′-phenylthiourea derivative 2 was synthesized
and then treated with variety of hydrazonoyl chlorides under basic condition at reflux to …
and then treated with variety of hydrazonoyl chlorides under basic condition at reflux to …
[HTML][HTML] Synthetic and biological studies of pyrazolines and related heterocyclic compounds
M Yusuf, P Jain - Arabian Journal of Chemistry, 2014 - Elsevier
This review provides a comprehensive survey relating to the synthesis and biological
applications of pyrazolines and related heterocycles in the last five years (2007–2011) …
applications of pyrazolines and related heterocycles in the last five years (2007–2011) …
Regioselective synthesis and computational calculation studies of some new pyrazolyl‐pyridine and bipyridine derivatives
Abstract Starting from 3‐oxo‐N‐(3‐pyridyl) butanamide, as key intermediate, the title
compounds were synthesized in good yields. Reaction of the pyridine‐carboxamide 1 with …
compounds were synthesized in good yields. Reaction of the pyridine‐carboxamide 1 with …
Design, synthesis and molecular modeling of pyrazole–quinoline–pyridine hybrids as a new class of antimicrobial and anticancer agents
CB Sangani, JA Makawana, X Zhang… - European Journal of …, 2014 - Elsevier
A new series of pyrazole–quinoline–pyridine hybrids were designed based on molecular
hybridization technique and synthesized by a base-catalyzed cyclocondensation reaction …
hybridization technique and synthesized by a base-catalyzed cyclocondensation reaction …
Synthesis and antiviral activity of some new bis-1, 3-thiazole derivatives
Abstract Treatment of 3-phenyl-1, 3-thiazolidin-4-one derivative 1 with phenylisothiocyanate
in DMF, in the presence of potassium hydroxide, at room temperature gave the non-isolable …
in DMF, in the presence of potassium hydroxide, at room temperature gave the non-isolable …
Synthesis of novel mono-and bis-pyrazolylthiazole derivatives as anti-liver cancer agents through EGFR/HER2 target inhibition
Bromoacetyl-4-(2-naphthoyl)-1-phenyl-1H-pyrazole (6) was synthesized from 2-
acetylnaphthalene and was used as a new key building block for constructing the title …
acetylnaphthalene and was used as a new key building block for constructing the title …
Antiproliferative activity and molecular docking studies of new 4-oxothiazolidin-5-ylidene acetate derivatives containing guanylhydrazone moiety
A new series of 4-oxothiazolidin-5-ylidene acetates (1–16) containing guanylhydrazone
moiety were designed and synthesized by using dimethyl acetylenedicarboxylate (DMAD) …
moiety were designed and synthesized by using dimethyl acetylenedicarboxylate (DMAD) …